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American Heart Association Funding Opportunities

American Heart Association Funding Opportunities. Annie Oliveto Director of Research. Who We Are. AHA is the largest funding source for CVD/Stroke research other than the NIH. Founded in 1924—close to $3 billion spent on research, $1 billion in the last 10 years alone.

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American Heart Association Funding Opportunities

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  1. American Heart Association Funding Opportunities Annie Oliveto Director of Research

  2. Who We Are • AHA is the largest funding source for CVD/Stroke research other than the NIH. • Founded in 1924—close to $3 billion spent on research, $1 billion in the last 10 years alone. • Last year AHA spent $152 million in research, $11.8 was through the Western States Affiliate. • AHA spends more on research (by percentage) than any other non-profit health organization.

  3. Research Funding 75% 25% Donor Dollar National Center Western States 21% 15% Research Allocation

  4. Breakthroughs Funded by AHA • The first artificial heart valve. • Techniques and standards for CPR • Implantable pacemakers to • regulate irregular • heartbeats. • Heart-lung machine • Cholesterol inhibitors • On top of research innovations, the AHA has created programs to implement science: Get With the Guidelines, • medical journals, conferences, professional and public education

  5. Breakthroughs Still Needed in CVD Research • Obesity and cholesterol reduction • Modify behaviors leading to CVD and Stroke • Diabetes and heart disease • Congenital heart defects • CVD/ Stroke in African Americans and other ethnic groups • Strategies to understand and treat • heart failure • Gene studies • Abnormal heart rhythms

  6. Breakthroughs Still Needed in Stroke Research • Stroke Treatments • Brain Imaging Techniques • Stroke Risk Factors, Education & Awareness • Stroke and Dementia • Recovery from Stroke • Gene and Protein Research

  7. AHA’s Research Focus • Training and career development of • beginning scientists • Support of cutting • edge basic and • clinical science

  8. What Kinds of Research Do We Support? The AHA supports research that is broadly related to the cardiovascular area and stroke.

  9. Application submitted Critique developed $ Funded Research completed Findings translated Life Cycle of a Research Application Assigned to Reviewers Idea Begins Rank Ordered List Developed Peer Review Reports Published

  10. Western Review ConsortiumPeer Review Committees

  11. Western States AffiliatePromotes Careers in Research STUDENT RESEARCH PROGRAMS Undergraduate Student Research Program Encourages research careers related to the cardiovascular or cerebrovascular areas. $4K – 10 weeks Medical Student Research Award Provides an opportunity to explore a research career related to the cardiovascular area or stroke. $600/wk – 8-12 weeks

  12. Western States AffiliatePromotes Careers in Research FELLOWSHIP AWARDS Predoctoral Fellowships - Undergraduate Students Initiates careers in cardiovascular and stroke research and supports doctoral dissertation projects. $18,500/yr – 2-3 years Postdoctoral Fellowship - PhD and MD trainees Initiates careers in cardiovascular and stroke research, and furthers research training while obtaining significant research results. $30K-46K/yr – 2-3 years

  13. GRANTS Beginning-Grant-In-Aid – Beginning Scientists Promotes independent status and supports high quality research projects. $70K/yr – 2-4 years Grant-In-Aid -- Independent Investigators Supports the most innovative and meritorious research. $70K/yr – 2-4 years *AHA National offers Scientist Development Grants, Fellow to Faculty, Established Investigator Awards and Clinical Research Awards

  14. Behavior Studies Biomedical Ethics Cardiac Rehabilitation Clinical Trials Compliance Coping Strategies / Stress Mgt Depression Epidemiology Exercise / Physical Activity Familial Aggregation / Genetic Epidemiology Health Care Utilization/Cost Effectiveness Health Promotion/Prevention Human Nutrition (Behavioral and Preventive Aspects) Obesity Nutrition Outcomes Research Preventive Cardiology Quality of Life Social Support Systems Stroke Weight Control Did you know that the AHA Funds:

  15. Areas Ineligiblefor AHA Funding HUMAN EMBRYONIC orFETAL STEM CELLSAND HUMAN FETAL TISSUE or HUMAN CLONING Ineligible for funding: • Cloning of humans as asexual reproduction or cloning of humans intended as sources of tissue or organs to harvest are not acceptable. Ineligible for funding: • Derivation or use of human stem cells from in vitro fertilization (IVF) treatment embryos or fetal sources. • Use of human fetal tissue.

  16. FATAL FLAWSCommon MistakesMade When Applyingfor Funding

  17. FATAL FLAWSby Investigators • No demonstration of expertise or publications in approaches, low productivity • No collaborators recruited or no letters from collaborators • Unnecessary experimental detail • Not enough detail on approaches, especially untested ones • Not enough preliminary data to establish feasibility, nor any correlative or descriptive data • Feasibility of each aim not shown • Little or no expertise with approach • Lack of appropriate controls • Not directly testing hypothesis

  18. FATAL FLAWSSignificance • Not significant nor exciting nor new research • Lack of compelling rationale • Incremental and low impact research • Innovation is not always necessary, but the results should have compelling significance • Little demonstration of institutional support • Little or no start up package or necessary equipment

  19. FATAL FLAWSResubmissions • Insulting the reviewers • Only responding to specific reviewer concerns and not other aspects that may be newly criticized • Just changing the name or submitting a previous project as new • Do not send the same or similar application for review without indicating that it is a resubmission • AHA allows 2 resubmssions + Original allowed

  20. DEADLINESTake them seriously! • ~5% are administratively withdrawn each year (NIH and AHA) • Technical problems? Call before the 5:00 pm deadline. • Applications received after 5:00pm are administratively withdrawn. • Acknowledgement of receipt should be received within 24 hours after electronic submission. • READ the acknowledgement for possible errors in electronic upload of your application.

  21. Late Applications • Contact AHA staff before deadline if experiencing problems with the electronic website. • Late paper copies may be accepted for genuine reasons and if electronic submission was on time.

  22. Administrative Withdrawal • Late electronic or paper copies • Modifications after deadline • Format issues: • type size • characters per inch (CPI) • lines per page • exceeding page limits

  23. Streamlined Review“Triage” • Removes noncompetitive applications from the review process • Applicants receive critiques, but not scores • Applies to fellowships and grants • 40% of consortia applications can be triaged

  24. PREDOCTORAL FELLOWSHIP APPLICANTS Describe undergraduate/ graduate research activities: • research participation programs • student-originated study programs • research gained through summer or part-time employment • research within course work and/or outside of the classroom Summarize, stating problems studied and conclusions reached

  25. Technical Support • Request technical assistance from AHA • Seek advice on administrative issues from your grants management specialist

  26. Questions and Answers Annie Oliveto 650-259-6715 Annie.Oliveto@heart.org

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