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Lesson 7 – Cancer Cells

Lesson 7 – Cancer Cells. 1.2 Cell Growth and the cell cycle. Bell Task. Mitotic index?. 12%. Cancer Cells. Cancer Explained using cells under the microscope (8 mins ). Cancer cells have lost control of the cell cycle. There are 2 main classes of genes responsible for this loss of control:

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Lesson 7 – Cancer Cells

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  1. Lesson 7 – Cancer Cells 1.2 Cell Growth and the cell cycle

  2. Bell Task Mitotic index? 12%

  3. Cancer Cells Cancer Explained using cells under the microscope (8 mins) Cancer cells have lost control of the cell cycle. There are 2 main classes of genes responsible for this loss of control: Proliferation genes Antiproliferation genes

  4. Proliferation Genes Proliferation genes (also called proto-oncogenes) code for proteins that promote cell division. Overexpression results in too much cell division. When mutated these genes are called oncogenes. A mutation only has to happen in one gene of the pair so these genes are often considered as dominant.

  5. Antiproliferation Genes Antiproliferation genes are the genes that code for proteins that tell a cell to stop dividing. These genes are also known as tumour suppressing genes. Mutations must take place in both alleles of an anti-proliferation gene for loss of cell cycle control to occur. This is therefore considered a recessive trait.

  6. What is a tumour? A tumour is a growth of undifferentiated cells. Not all tumours will become cancerous. A tumour that is not cancerous is called a benign tumour. A tumour that is cancerous is called a malignant tumour. Cells from malignant tumours may undergo metastasis which involves entering the circulation and then forming new tumours in another part of the body.

  7. Your Task Read pages 12 – 14 in the student monograph and take notes. Add the red terms from this powerpoint to your glossary with detailed definitions. Complete all of the Scholar online activities for Prokaryotic and Eukaryotic Cells. (note: your next lesson is not until Mon Sept 24th)

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