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Fig. 1. BT-474. MCF-7. SK-BR-3. MDA-MB-231. A. β- actin. cyclin B1. C. C. C. C. Cdk1. siRNA1. siRNA1. siRNA1. siRNA1. siRNA3. siRNA3. siRNA3. siRNA3. siGFP. siGFP. siGFP. siGFP. BT-474. MDA-MB-231. MCF-7. SK-BR-3. 1,6. cyclin B1 relative protein level. 1,2. 0,8.
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Fig. 1 BT-474 MCF-7 SK-BR-3 MDA-MB-231 A β-actin cyclin B1 C C C C Cdk1 siRNA1 siRNA1 siRNA1 siRNA1 siRNA3 siRNA3 siRNA3 siRNA3 siGFP siGFP siGFP siGFP BT-474 MDA-MB-231 MCF-7 SK-BR-3 1,6 cyclin B1 relative protein level 1,2 0,8 0,4 0 B 160 BT-474 C C C C siRNA1 120 siRNA1 siRNA1 siRNA3 siRNA1 siRNA3 siRNA3 siRNA3 siGFP siGFP siGFP siGFP relative kinase activity (%) 80 40 0 IgG C siGFP siRNA1