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Bioterrorism Workbook and Decision Support: The Pittsburgh Matrix. Michael Allswede, D.O. Section Chief Special Emergency Medical Response University of Pittsburgh Medical Center Health System. Pittsburgh Matrix.
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Bioterrorism Workbook and Decision Support: The Pittsburgh Matrix Michael Allswede, D.O. Section Chief Special Emergency Medical Response University of Pittsburgh Medical Center Health System
Pittsburgh Matrix • Provide a decision support tool for hospitals and hospital systems preparing for or responding to bioterrorism events • Provide a method of determining value for bioterrorism capability • Guide funding for hospital capability development
The Pittsburgh Matrix:Medical Decision-Making Allswede, MP, Watson SJ., AHRQ Partnership for Quality, 2002
Pathogen Rating • Communicability/Quarantine Needs • 0: Non-communicable/No Quarantine Example: Bot Toxin • 1: Blood and Body Fluid/Universal Precautions Example: HIV Virus • 2: Close Contact/Universal Precautions Example: Ebola Virus • 3: Airborne/HEPA Filtration Example: Variola Virus • Effectiveness of Medical Treatment • 0: Comfort Measures Only Needed Example: Salmonella • 1: Highly Effective-Survival Probable Example: Skin Anthrax • 2: Improved Survival-Survival Improved Example: Yersinia Pestis • 3. Ineffective-Survival Not Improved Example: Variola Virus • Availability of Medical Treatment • 0: Non-Pharmaceutical Treatment Example: Clear Liquid Diet • 1: Multiple Available Pharmaceuticals Example: Ames Strains • 2: Insufficient Local Supply Pharmaceutical Example: Bot Antitoxin • 3: Obscure or Experimental Pharmaceuticals Example: Variola Vaccine Allswede, MP, Watson SJ., AHRQ Partnership for Quality, 2002
Effects of Preparedness Better Technology System Preparedness Allswede, MP, Watson SJ., AHRQ Partnership for Quality, 2002
Anthrax Aerosol Note: Numbers represent pathogen scores (Percentages) represent estimated mortality rates Allswede, MP, Watson SJ., AHRQ Partnership for Quality, 2002 Allswede, MP, Watson SJ., AHRQ Partnership for Quality, 2002
Variola Note: Numbers represent pathogen scores (Percentages) represent estimated mortality rates Allswede, MP, Watson SJ., AHRQ Partnership for Quality, 2002
Decision Support Tool • Each Medical Asset can determine capacity levels based on daily census, surge disaster planning, and community outreach • Timeline will be evident so a given box can be accessed • Each box has Key Decisions and Key Resources enumerated in a logical response hierarchy
Resource Valuation • Key Resources (capabilities) within each matrix box are accounted using UPMC Health System data • Survivorship estimates yield value in dollars/lives saved for each matrix Key Resource
Pittsburgh Matrix: Work to do • Complete methodological workbook for other medical facilities to follow • Estimation of probability of a given attack occurrence • EX: World events change the threshold and likelihood of each given attack • Estimation of detection capability of a given attack • EX: Syndromic detection is better for larger scale events
For More Information AHRQ-sponsored Workbook for Regional Bioterrorism Preparedness A collaborative effort between Research Triangle Institute, UPMC Health Systems, and Intermountain Health Care Available: September 30, 2003 Contact: Lucy Savitz at savitz@rti.org