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CORE CLOCK COMPONENTS IN FEEDBACK LOOPS OF 3 SYSTEMS

MCB 186 CIRCADIAN BIOLOGY Clock genes & Biochemical Mechanisms: Kai genes October 10, 2007 J. W. Hastings. CORE CLOCK COMPONENTS IN FEEDBACK LOOPS OF 3 SYSTEMS. TEMPORAL SEPARATION OF CELL BIOCHEMICAL ACTIVITIES IN CYANOBACTERIA ( OXYGEN, NITROGENASE ETC) MITSUI ET AL 1986.

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CORE CLOCK COMPONENTS IN FEEDBACK LOOPS OF 3 SYSTEMS

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  1. MCB 186CIRCADIAN BIOLOGYClock genes & Biochemical Mechanisms: Kai genesOctober 10, 2007J. W. Hastings

  2. CORE CLOCK COMPONENTS IN FEEDBACK LOOPS OF 3 SYSTEMS

  3. TEMPORAL SEPARATION OF CELL BIOCHEMICAL ACTIVITIES IN CYANOBACTERIA (OXYGEN, NITROGENASE ETC)MITSUI ET AL 1986

  4. CIRCADIAN RHYTHM of CYANOBACTERIAL GENE mRNA Kondo et al. 1993 PNAS LUCIFERASE REPORTER

  5. Turntable Screening Apparatus: 12 positions for petri dishes or titer plates

  6. BACTERIAL COLONIES EXPRESSING BIOLUMINESCENCE Kondo et al. 1993 PNAS

  7. Cyanobacterial in vivo Rhythm with Bacterial Luciferase as a Reporter Luminescence Kondo, Johnson Golden et al., 1993, PNAS

  8. EFFECT OF DARK EXPOSURES ON PERIOD In light but with 3 min in dark every 30 min In LL during ----

  9. DARK PULSE PHASE SHIFTS IN CYANOBACTERIA KONDO ET AL 1993

  10. TEMPERATURE has SMALL EFFECT on PERIOD of BACTERIAL RHYTHM

  11. PERIOD MUTANTS OF CYANOBACTERIAKONDO ET AL.1995

  12. CYANOBACTERIA ARHYTHYMIC & AMPLITUDE MUTANTS KONDO 1995

  13. PERIOD VARIATION OF INDIVIDUAL CYANOBACTERIA MUTANT CLONESKONDO ET AL.1995

  14. LUCIFERASE REPORTER RANDOMLY INSERTED IN FRONT OF PROMOTERS IN BACTERIA.ABOUT 800 LUMINOUS COLONIES ISOLATEDALL EXHIBITED CIRCADIAN RHYTHMSACROPHASES NOT ALL THE SAME

  15. ACROPHASE CLASSES OF CLOCK-CONTROLLED GENES LIU ET AL ,1995

  16. KAI genes in SYNECHOCOCCUS and MUTANT MAPPINGISHIUR

  17. PHENOTYPES OF KAI GENE INACTIVATIONS ISHIURA ET AL 1998

  18. EXPRESSION OF KAI GENE CONSTRUCTS ISHIURA ET AL 1998

  19. Cyanobacterial Clockworks TTO Model -1998 Ishiura et al., 1998

  20. Cyanobacterial Clockwork Model TRANSCRIPTIONAL CONTROL OF MANY GENES 2003 Xu et al., EMBO J. 22: 2117-2126, 2003

  21. Kai C PHOSPHORYLATION RHYTHMin vitro in a SOLUTION CONTAINING only ATP with Kai A, B and CPhase is not determined by light Nakajima et al, Science, 308: 414-415 (2005 )

  22. IN VITRO CIRCADIAN RHYTHM KaiC PHOSPHORYLATION

  23. In vitro phosphorylation rhythm is temperature compensated Nakajima, M et al Kondo, T (2005) Reconstitution of circadian oscillation in vitro Science 308: 414-415

  24. In vitro phosphorylation rhythm is temperature compensated Nakajima, M et al Kondo, T (2005) Reconstitution of circadian oscillation in vitro Science 308: 414-415

  25. Period of phosphorylation rhythm corresponds to mutant periodTomita, Nakajima, Kondo & Iwasaki (2005)Science 307: 251-254

  26. Tau of in vitro P-oscillation corresponds to mutant tau Nakajima, M et al Kondo,T (2005) Reconstitution of circadian oscillation in vitro Science 308: 414-415

  27. Simplified model for the posttranslational oscillator Nakajima, M et al Kondo,T (2005) Science 308: 414-415

  28. EVIDENCE THAT TRANSCRIPTION and TRANSLATION are not NECESSARY for CIRCADIAN OSCILLATIONSIN CYANOBACTERIATomita, Nakajima, Kondo & Iwasaki (2005) No transcription-translation feedbackin circadian rhythm of KaiC phosphorylation Science 307: 251-254

  29. NO RHYTHM OF kaiA or kaiBC mRNAs in DD Tomita, Nakajima, Kondo & Iwasaki (2005) No transcription-translation feedback in circadian rhythm of KaiC phosphorylation Science 307: 251-254

  30. NO RHYTHM OF KaiC PROTEIN in DDTomita, Nakajima, Kondo & Iwasaki (2005)Science 307: 251-254

  31. RHYTHM OF KaiC PROTEIN PHOSPHORYLATION in DDTomita, Nakajima, Kondo & Iwasaki (2005)Science 307: 251-254

  32. Period Temperature Compensation of in vivo Rhythm of KaiC Phosphorylation in DD Tomita, Nakajima, Kondo & Iwasaki (2005) No transcription-translation feedback in circadian rhythm of KaiC phosphorylation Science 307: 251-254

  33. Model for the posttranslational oscillator coupled with TTO Tomita, Nakajima, Kondo & Iwasaki (2005) No transcription-translation feedbackin circadian rhythm of KaiC phosphorylation Science 307: 251-254

  34. Tau of in vitro P-oscillation corresponds to mutant tau Nakajima, M et al Kondo, T (2005) Reconstitution of circadian oscillation in vitro Science 308: 414-415

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