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Echocardiographic Assessment of the Right Heart in Adults

Echocardiographic Assessment of the Right Heart in Adults. A Report from the American Society of Echocardiography, 2010. Learning Objectives. Describe the conventional two-dimensional acoustic windows required for optimal evaluation of the right heart

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Echocardiographic Assessment of the Right Heart in Adults

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  1. Echocardiographic Assessment of the Right Heart in Adults A Report from the American Society of Echocardiography, 2010

  2. Learning Objectives • Describe the conventional two-dimensional acoustic windows required for optimal evaluation of the right heart • Describe the echocardiographic parameters required in routine and directed echocardiographic studies, and the views to obtain these parameters for assessing right ventricular size and function • Identify the advantages and disadvantages of each measure or technique as supported by the available literature • Recognize which right sided measures should be included in the standard echocardiographic report • Explain the clinical and prognostic significance of right ventricular assessment

  3. Discussion • The right ventricle plays an important role in the morbidity and mortality of patients presenting with signs and symptoms of cardiopulmonary disease • Systematic assessment of right heart not uniformly carried out • Enormous attention given to left heart • Lack of familiarity with u/s techniques that can be used to assess the right heart • Scarcity of u/s studies providing normal reference values

  4. Executive summary • In all routine studies, the sonographer and physician should examine the right heart using multiple windows • The report should represent an assessment based on qualitative and quantitative parameters • The report should include a measure of • RV size • RA size • RV systolic function • PASP

  5. Basic views

  6. Basic views

  7. Basic views

  8. Segmental Nomenclature of RV walls

  9. Right heart dimensions • Right ventricle-focused apical 4 chamber view • Measured at end-diastole Sensitivity of angular change despite similar size and appearance of the left ventricle

  10. Right ventricular dimensions Basal RV diameter Mid cavitary RV diameter RV longitudinal dimension • 4.2 cm indicates dilatation • 3.5 cm indicates dilatation • 8.6 cm indicates RV enlargement

  11. RV linear dimensions Advantages Disadvantages • Linear dimensions are easily obtained on apical 4 chamber view • Good markers of RV dilatation • RV dimensions are highly dependent on probe rotation by the user • Can result in underestimation of RV width

  12. Recommendation “Patients with echocardiographic evidence of right-sided heart disease of PH should ideally have measurements of RV basal, mid cavitary, and longitudinal dimensions on a 4-chamber view. In all complete echocardiographic studies, the RV basal measurement should be reported and the report should state the window from which the measurement was performed (ideally the right ventricle-focused view), to permit interstudy comparisons.”

  13. Right atrial assessment • Apical 4-chamber view • Estimation of right atrial area by planimetry The maximum long distance of the RAis from the center of the tricuspid annulus to the superior RA wall, parallel to the interatrial septum A mid RA minor distancve is defined from the mid level of the RA free wall to the interatrial septum perpendicular to the long axis RA area is traced at the end of ventricular systole, excluding the IVC, SVC, and RAA Normal area < 18 cm²

  14. Advantages Disadvantages • Ra dimensions and area are easily obtained on an apical 4 chamber view • Good markers of RA dilatation • RA area is more time consuming than linear dimensions alone

  15. Recommendation • Images adequate for RA area estimation should be obtained in patients undergoing evaluation for RV or LV dysfunction • RA dimensions should be considered in all patients with significant RV dysfunction in who image quality does not permit for the measurement of RA area Note: RA volume measurements have not been standardized and are not currently recommended

  16. RA pressure determination • Measurement of the IVC should be obtained at end-expiration and just proximal to the junction of the hepatic veins that lie approximately 0.5 to 3.0 cm proximal to the ostium of the right atrium To accurately assess IVC collapse, the change in diameter of the IVC with a sniff and also with quiet respiration should be measured, ensuring that the change in diameter does not reflect a translation of the IVC into another plane

  17. Recommendations

  18. RV Wall Thickness • Useful measurement of RVH • From the subcostal view, align the u/s beam perpendicular to the RV free wall • Exclude RV trabeculations and papillary muscle from endocardial border • Moving the focus to the RV wall region and decreasing the depth will improve endocardial border definition • When imaging quality permits use fundamental frequency Normal < 0.5 cm

  19. RV Wall Thickness Advantages Disadvantages • RV wall thickness can be measured by M-mode or 2D echocardiography • It can be measured either from the subcostal or left parasternal window • There is a lack of established prognostic information

  20. Recommendation • Abnormal RV wall thickness should be reported, if present, in patients suspected of having RV and/or LV dysfunction

  21. RVOT measurement • Best viewed from left parasternal and subcostal windows • Should be measured at end-diastole on the QRS deflection Normal 1.7-2.7 cm

  22. RVOT measurement Advantages Disadvantages • RVOT dimensions are easily obtained from the left PSAX window • Certain lesions may primarily affect the RVOT • Limited normative data are available • The window for measurement of RVOT size has not been standardized • Oblique imaging of the RVOT may underestimate or overestimate its size • The endocardial definition of the anterior wall is often suboptimal

  23. Recommendation • On select patients with congenital heart disease or arrhythmia potentially involving the RVOT, proximal and distal diameters of the RVOT should be measured from the PSAX or PLAX views • The PSAX distal RVOT diameter, just proximal to the pulmonary annulus, is the most reproducible and should be generally used • Cases of suspected ARRVC, the PLAX measure maybe added

  24. RV systolic function • All studies should include a measure of RV systolic function using at least one of the following: • Fractional area change (FAC) • Tricuspid annular plane systolic excursion (TAPSE) • S´ • One of these measurements should be reported with or without • RV index of myocardial performance (RIMP)

  25. Fractional area change • Defined as • RV FAC correlates well with RV EF by MRI • RV FAC found to be independent predictor of heart failure, sudden death, stroke, and/or mortality in studies of patients after pulmonary embolism End diastolic area – End systolic area X 100 End-diastolic area

  26. RV FAC • Obtained by tracing RV endocardium both in systole and diastole from the annulus, along the free wall to the apex, and then back to the annulus, along the interventricular septum • Avoid trabeculations Normal > 35 %

  27. Recommendation • 2D Fractional Area Change is one of the recommended methods of quantitatively estimating RV function

  28. TAPSE or TAM • Acquired by placing an M-mode cursor through the tricuspid annulus and measuring the amount of longitudinal motion of the annulus at peak systole Normal > 16 mm

  29. TAPSE Advantages Disadvantages • TAPSE is simple • Less dependent on optimal image quality • Reproducible • Does not require sophisticated equipment or prolonged image analysis • TAPSE assumes that the displacement of a single segment represents the function of a complex 3D structure • It is angle dependent • There are no large scale validation studies • TAPSE maybe load dependent

  30. Recommendation • TAPSE should be used routinely as a simple method of estimating RV function

  31. Tissue Doppler Imaging • An apical four chamber view is used • The pulsed Doppler sample volume is placed in either the tricuspid annulus or the middle of the basal segment of the RV free wall • The S´ velocity is read as the highest systolic velocity without over-gaining the Doppler envelope Normal > 10 cm/s

  32. Tissue Doppler (S´) Advantages Disadvantages • A simple, reproducible technique with good discriminatory ability to detect normal versus abnormal RV function • Pulsed Doppler is available on all modern systems • Maybe obtained and analyzed off-line • Less reproducible for nonbasal segments • Is angle dependent • Limited normative data in all ranges' and in both sexes • It assumes that the function of a single segment represents the function of the entire right ventricle

  33. Recommendation • Interrogation of S´ by pulsed tissue Doppler is a simple and reproducible measure to assess basal RV free wall function and should be used in the assessment of RV function

  34. RV IMP (Tei Index) • RV index of Myocardial Performance • Global index of both systolic and diastolic function of the right ventricle IVRT + IVCT ET Normal < 0.40 Normal < 0.55

  35. Advantages Disadvantages • This approach is feasible in a large majority of subjects • The MPI is reproducible • It avoids geometric assumptions and limitations of the complex RV geometry • The pulsed TDI method allows for measurement of MPI as well as S´, E´, and A´ all from a single image • The MPI is unreliable when RV ET and TR time are measured with differing R-R intervals, as in atrial fibrillation • It is load dependent and unreliable when RA pressures are elevated

  36. Recommendation • The MPI may be used for initial and serial measurements as an estimate of RV function in complement with other quantitative and qualitative measures • It should not be used as the sole quantitative method for evaluation of RV function and should not be used with irregular heart rates

  37. RV Strain and Strain rate • Due to the lack of normative data and the lack of reproducibility, these methods are not recommended for routine clinical use

  38. RV Diastolic Function • From the apical 4-chamber view, the Doppler beam should be aligned parallel to RV inflow • Sample volume is placed at the tips of the tricuspid valve leaflets • Measure at held end-expiration and/or take the average of ≥ 5 consecutive beats • Measurements are essentially the same as those used for the left side

  39. RV Diastolic Function

  40. Recommendation • Measurement of RV diastolic function should be considered in patients with suspected RV impairment as a marker of early or subtle RV dysfunction, or in patients with known RV impairment as a marker for poor prognosis • Transtricupsid E/A ratio, E/E’ ratio, and RA size have been most validated are the preferred measures

  41. Other Recommendations • Visual assessment of ventricular septal curvature looking for a D-shaped pattern in systole and diastole should be used to help in the diagnosis of RV volume an/or pressure overload RV pressure overload-septal shift throughout cardiac cycle with most marked distortion of LV at end systole RV volume overload-septal shift occurs predominately in mid to late diastole

  42. Other Recommendations • SPAP should be estimated and reported in all subjects with reliable tricuspid regurgitant jets • Discourages use of contrast as it obscures the clear envelope

  43. Other Recommendations • Mean PA pressure • Whenever possible, it is helpful to use several methods to calculate mean pressure so that the internal consistency of the data can be challenged and confirmed. Methods to use: 1. Mean PA pressure = 2. Mean PA pressure = 79 – (0.45 x AT) 1/3 (SPAP) + 2/3 (PADP) 90 – (0.62 x AT) 3. Mean PA pressure = 4 x (early PR vel²) + est. RAP 4. Mean PA pressure =

  44. Mean PA Pressure 4(early PR vel)² + est. RAP 4(3.05 m/sec)² + est. RAP Mean PAP= 37 mmHg + RAP 4(2.29 m/sec)² + est. RAP PADP = 21 mmHg + RAP

  45. Mean PA Pressure • In patients with PA hypertension or heart failure, an estimate of PADP from either the mean gradient of the TR jet or from the pulmonary regurgitant jet should be reported • If the estimated SPAP is > 35-40 mmHg, stronger scrutiny may be warranted to determine if PH is present, factoring in other clinical information

  46. Other Recommendations • Pulmonary Vascular Resistance “An elevation in SPAP does not always imply increased PVR. PVR distinguishes elevated pulmonary pressure due to high flow from that due to pulmonary vascular disease” • PVR can be estimated using the ratio of peak TR velocity to the RVOT VTI

  47. Pulmonary Vascular Resistance PVR = TRV max / RVOT TVI x 10 + 0.16 2.78 m/sec ÷ 11 cm x 10 + 0.16 = 2.68 Wood units Significant PHTN exists when PVR is > 3 Wood units

  48. PVR • The estimation of PVR is not adequately established to be recommended for routine use but may be considered in subjects in whom pulmonary systolic pressure may be exaggerated by high stroke volume or misleading low by reduced stroke volume • The noninvasive estimation of PVR should not be used as a substitute for the invasive evaluation of PVR when this value is an important guide to therapy

  49. RV dP/dt • The rate of pressure rise in the right ventricle • Estimated from the ascending limb of the tricuspid regurgitant CW Doppler signal • Measure the time required for the TR jet to increase in velocity from 1 to 2 m/s (represents a 12 mmHg increase) 30 ms or 0.03 seconds 12 mmHg / 0.03 seconds 400 mmHg/s RV dP/dt < 400 mmHg/s is likely abnormal

  50. RV dP/dt • Because of the lack of data in normal subjects, RV dP/dt cannot be recommended for routine uses. It can be considered in subjects with suspected RV dysfunction

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