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VIRUS MEANS “POISON”!. MADE OF PROTEIN AND NUCLEIC ACID (EITHER DNA or RNA) . Protein part is the CAPSID. NA is inside capsid. Living or Not? They have genetic material & structural proteins. BUT: No Ribosomes No Organelles No Nucleus Can’t Use Energy. AND: They Cannot
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VIRUS MEANS “POISON”!
MADE OF PROTEIN AND NUCLEIC ACID (EITHER DNA or RNA)
Protein part is the CAPSID NA is inside capsid
Living or Not? They have genetic material & structural proteins
BUT: No Ribosomes No Organelles No Nucleus Can’t Use Energy
AND: They Cannot Reproduce on their own
SO: They are NON-LIVING!
They are referred to as Obligate Intracellular Parasites
They need a HOST CELL in order to replicate.
They can be classified 3 Ways:
Polyhedron, Helical, Complex INTERESTING SHAPES!
Some are “enveloped” with a membrane- like structure
Their nucleic acid type: Either DNA or RNA virus
DNA virus:DNA is inserted into cell, then protein synthesis using virus mRNA
OR, Virus DNA joins host cell DNA and replicates with host cell DNA
RNA Virus: virus RNA is inserted into host cell,makes proteins directly
OR, RNA retrovirus: DNA, made by reverse transcription, joins host DNA, followed by protein synthesis
Classified by whether or not the virus is disease-causing
Virus can be “virulent”--causes disease right away (like a cold or flu)
If virulent, they undergo the LYTIC CYCLE
Lytic Cycle: 1) Adsorption: virus attaches to host cell
2) Entry: virus NA is injected into host cell
3) Replication: Host cell starts making virus parts
4) Assembly: virus parts get put together
5) Release: host cell gets so full of new viruses that it bursts, releasing viruses
Virus can be “temperate”--waits to cause disease later (like HIV)
a) If temperate, virus goes into the LYSOGENIC CYCLE
b) LYSOGENIC CYCLE: Starts like lytic cycle with adsorption & entry
c) Then, Attachment: virus DNA joins with host DNA
d) Replication: Host cell undergoes replication; virus DNA gets copied
e) Activation: something triggers the virus to become virulent (lytic)
Then,it starts the LYTIC CYCLE and causes infection (disease).
How are viruses spread? Bodily fluids Through air, water Direct contact
What is smaller than a virus? Viroid--NA only cause plant diseases
Prion--small strand of amino acids; mammal diseases like CWD or Mad Cow disease
How could you prevent viral infections? Vaccinations Wash hands! Cover your mouth when sneezing or coughing! Safe sex!