Depo-Provera Contraceptive Injection (Medroxyprogesterone Acetate Injection)

1. Depo-Provera Contraceptive Injection (Medroxyprogesterone Acetate Injection) © All Contraceptives

2. Depo-Provera Contraceptive Injection (Medroxyprogesterone Acetate Injection) Depo-Provera Contraceptive Injection (Medroxyprogesterone Acetate Injection) is s a progestin injectable contraceptive which is used to prevent pregnancy in women 18 years and above. This medication works by preventing the growth and release of an egg (ovulation) during the menstrual cycle. Medroxyprogesterone acetate hinders (in the usual dose range) the secretion of pituitary gonadotropin which, in turn, prevents follicular maturation and ovulation. © All Contraceptives

3. Depo-Provera Contraceptive Injection (Medroxyprogesterone Acetate Injection) © All Contraceptives

4. Depo-Provera Contraceptive Injection (Medroxyprogesterone Acetate Injection) Active Ingredient The active ingredient present in Depo-Provera Contraceptive Injection is is Medroxyprogesterone Acetate. Each injection (1 ml vial ) contains 150 mg of Medroxyprogesterone Acetate. © All Contraceptives

5. Depo-Provera Contraceptive Injection (Medroxyprogesterone Acetate Injection) Chemical Structure - Medroxyprogesterone Acetate © All Contraceptives

6. Depo-Provera Contraceptive Injection (Medroxyprogesterone Acetate Injection) © All Contraceptives

7. Depo-Provera Contraceptive Injection (Medroxyprogesterone Acetate Injection) Depo Provera Contraceptive Injections Depo-Provera Contraceptive Injections are manufactured by Pfizer in Belgium. Depo-Provera Contraceptive Injection for intramuscular (IM) injection is available in vials and prefilled syringes, each containing 1 mL of Medroxyprogesterone Acetate sterile aqueous suspension of strength 150 mg/mL. (Website: https://www.pfizer.com/ ) URL: https://www.allcontraceptives.com/depo-provera-injection.html © All Contraceptives

8. Depo-Provera Contraceptive Injection (Medroxyprogesterone Acetate Injection) Uses of Depo-Provera Contraceptive Injections Depo Provera Contraceptive Injection is a well-known brand name for Medroxyprogesterone Acetate, a contraceptive injection that contains the hormone progestin. Depo-Provera is given as an injection every three months. Depo-Provera typically suppresses ovulation, keeping your ovaries from releasing an egg. It also thickens cervical mucus to keep sperm from reaching the egg. Depo-Provera is used to prevent pregnancy and manage medical conditions related to your menstrual cycle. Your health care provider might recommend Depo-Provera if: you don't want to take a birth control pill every day, You want or need to avoid using estrogen, You have health problems such as anemia, seizures, sickle cell disease, endometriosis or uterine fibroids. URL: https://www.allcontraceptives.com/depo-provera-injection.html © All Contraceptives

9. Depo-Provera Contraceptive Injection (Medroxyprogesterone Acetate Injection) Recommended Dosage The dosage of Depo-Provera Contraceptive Injections (Medroxyprogesterone Acetate Injection) is given below: The recommended dosage of Depo-Provera Contraceptive Injection is 150 mg of Depo-Provera CI every 3 months (13 weeks) administered by deep IM injection in the gluteal or deltoid muscle. The 1 mL vial as well as the 1 mL prefilled syringe of Depo- Provera CI should be vigorously shaken just before use to ensure that the dose being administered represents a uniform suspension. URL: https://www.allcontraceptives.com/depo-provera-injection.html © All Contraceptives

10. Depo-Provera Contraceptive Injection (Medroxyprogesterone Acetate Injection) Contraindications Depo-Provera Contraceptive Injection is contraindicated in persons with a hypersensitivity (allergy) to Medroxyprogesterone Acetate or any of the other ingredients of this medicine. Depo-Provera CI is also contraindicated in known or suspected pregnancy or as a diagnostic test for pregnancy, Active thrombophlebitis, or current or past history of thromboembolic disorders, or cerebral vascular disease, Known or suspected malignancy of breast, significant liver disease and undiagnosed vaginal bleeding. URL: https://www.allcontraceptives.com/depo-provera-injection.html © All Contraceptives

11. Depo-Provera Contraceptive Injection (Medroxyprogesterone Acetate Injection) Before Taking This Medicine You may need to have a negative pregnancy test before you start Depo- Provera. You should not use Depo-Provera if you are pregnant, or if you have: abnormal vaginal bleeding that has not been checked by a doctor, liver disease, breast cancer; or a history of stroke or blood clot. Make sure Depo-Provera is safe for you, tell your doctor if you have ever had: light or irregular menstrual periods; risk factors for osteoporosis (such as low bone mineral density, a family history of osteoporosis, drinking large amounts of alcohol, or if you smoke); a breast lump, an abnormal mammogram, or bleeding from your nipples; kidney disease; high blood pressure; breast cancer (in you or a family member); URL: https://www.allcontraceptives.com/depo-provera-injection.html © All Contraceptives

12. Depo-Provera Contraceptive Injection (Medroxyprogesterone Acetate Injection) Before Taking This Medicine You should not use Depo-Provera if you are pregnant, or if you have: diabetes; depression, or an eating disorder; seizures; asthma or migraine headaches. Tell your doctor right away if you become pregnant, or if you plan to become pregnant soon after you stop using Depo-Provera CI. It may not be safe to breastfeed while using Depo-Provera. Ask your doctor about any risk. URL: https://www.allcontraceptives.com/depo-provera-injection.html © All Contraceptives

13. Depo-Provera Contraceptive Injection (Medroxyprogesterone Acetate Injection) Storage Instructions Depo-Provera Contraceptive Injection (Medroxyprogesterone Acetate Injection) have to be stored at controlled room temperature i.e. from 20°C to 25°C (68°F to 77°F) with excursions permitted between 15° to 30°C (59° to 86°F). Keep this as well as all other medicines away from children and pets. URL: https://www.allcontraceptives.com/depo-provera-injection.html © All Contraceptives

14. Depo-Provera Contraceptive Injection (Medroxyprogesterone Acetate Injection) Warnings Loss of Bone Mineral Density: Use of Depo-Provera CI decreases serum estrogen levels and is associated with significant loss of bone mineral density (BMD) as bone metabolism accommodates to a lower estrogen level. Bleeding Irregularities: Most women using Depo-Provera Contraceptive Injection experience disruption of menstrual bleeding patterns. Changed menstrual bleeding patterns also include irregular or unpredictable bleeding or spotting, or rarely, heavy or continuous bleeding. Thromboembolic Disorders: The doctor must be alert to the earliest manifestations of thrombotic disorders (thrombophlebitis, pulmonary embolism, cerebrovascular disorders, and retinal thrombosis). Ocular Disorders: Depo-Provera must not be readministered pending examination in case there is a sudden partial or complete loss of vision or if there is a sudden onset of proptosis, diplopia, or migraine. © All Contraceptives

15. Depo-Provera Contraceptive Injection (Medroxyprogesterone Acetate Injection) Warnings Unexpected Pregnancies: To make sure that Depo-Provera CI is not administered inadvertently to a pregnant woman, the first injection must be given ONLY during the first 5 days of a normal menstrual period; ONLY within the first 5-days postpartum if not breast-feeding, and in case exclusively breast-feeding, ONLY at the sixth postpartum week. Ectopic Pregnancy: Doctors must be alert to the possibility of an ectopic pregnancy among women using Depo-Provera CI who become pregnant or complain of severe abdominal pain. Lactation: Detectable amounts of Medroxyprogesterone Acetate have been identified in the milk of mothers receiving Depo Provera Contraceptive Injection. Anaphylaxis and Anaphylactoid Reaction: Anaphylaxis and anaphylactoid reaction have been reported with the use of Depo Provera Contraceptive Injection. In cae an anaphylactic reaction occurs appropriate treatment should be started. Serious anaphylactic reactions require emergency medical treatment. © All Contraceptives

16. Depo-Provera Contraceptive Injection (Medroxyprogesterone Acetate Injection) Overdose In case of patients with a mild overdose, it is possible that no symptoms may occur. Depo-Provera CI overdose Symptoms are more likely to occur with high doses, or when too much Depo-Provera is used over a long period of time. Symptoms of an overdose can includeHeadache, Dizziness, Yellowing of the skin or the whites of the eyes (jaundice), Irregular menstruation, such as spotting or heavier or lighter periods, Breast pain, Bloating, Depression and Decreased libido (sex drive). Treatment for a Depo- Provera overdose will normally involve supportive care, which consists of treating the symptoms that occur as a result of an overdose. URL: https://www.allcontraceptives.com/depo-provera-injection.html © All Contraceptives

17. Depo-Provera Contraceptive Injection (Medroxyprogesterone Acetate Injection) Depo-Provera Contraceptive Injection During Pregnancy Medroxyprogesterone Acetate Injection (Depo-Provera Contraceptive Injection) is classified by the US FDA as Pregnancy Category X. This medicine is contraindicated in pregnancy. URL: https://www.allcontraceptives.com/depo-provera-injection.html © All Contraceptives

18. Depo-Provera Contraceptive Injection (Medroxyprogesterone Acetate Injection) For more details on Depo-Provera Contraceptive Injection click here Depo-Provera Contraceptive Injection (Medroxyprogesterone Acetate Injection) by Pfizer in Belgium. URL: https://www.allcontraceptives.com/depo-provera-injection.html © All Contraceptives