Mirena IUD (Levonorgestrel Intrauterine Device)

1. Mirena IUD (Levonorgestrel Intrauterine Device) © All Contraceptives

2. Mirena IUD (Levonorgestrel Intrauterine Device) Mirena IUD (Levonorgestrel Intrauterine Device) is used for prevention of pregnancy for up to 8 years. This device must be replaced after the end of the eighth year. Mirena is also indicated for the treatment of heavy menstrual bleeding for up to 5 years in women who choose to use intrauterine contraception as their method of contraception. You must replace after the end of the fifth year if continued treatment of heavy menstrual bleeding is needed. © All Contraceptives

3. Mirena IUD (Levonorgestrel Intrauterine Device) Active Ingredient The active pharmaceutical ingredients contained in Mirena Intrauterine Device is Levonorgestrel. Mirena Intrauterine Device consists of one sterile intrauterine system consisting of a T-shaped polyethylene frame with a steroid reservoir containing 52 mg Levonorgestrel packaged within a sterile inserter. © All Contraceptives

4. Mirena IUD (Levonorgestrel Intrauterine Device) Chemical Structure - Levonorgestrel © All Contraceptives

5. Mirena IUD (Levonorgestrel Intrauterine Device) © All Contraceptives

6. Mirena IUD (Levonorgestrel Intrauterine Device) Mirena Intrauterine Device Mirena IUD (Levonorgestrel Intrauterine Device) is manufactured by Bayer, Finland and market by Bayer Zydus Pharma Pvt. Ltd., India (Website: https://www.bayerzyduspharma.com/en/ https://www.bayerzyduspharma.com/en/ ) URL: URL: https://www.allcontraceptives.com/mirena-iud.html https://www.allcontraceptives.com/mirena-iud.html © All Contraceptives

7. Mirena IUD (Levonorgestrel Intrauterine Device) Uses of Mirena Intrauterine Device Mirena IUD gives long-term birth control for up to 8 years. You may use this IUD whether you have children or not. Mirena is also used for up to 5 years to treat heavy menstrual bleeding in women who choose to use an intrauterine form of birth control. The Mirena IUD releases Levonorgestrel in the uterus, but only small amounts of the hormone reach the bloodstream. URL: URL: https://www.allcontraceptives.com/mirena-iud.html https://www.allcontraceptives.com/mirena-iud.html © All Contraceptives

8. Mirena IUD (Levonorgestrel Intrauterine Device) Recommended Dosage The dosage of Mirena IUD Mirena IUD (Levonorgestrel Intrauterine Device) is given below: MIRENA is to be inserted by a trained healthcare provider using strict aseptic technique. Following insertion into the uterine cavity, MIRENA is effective for conception control up to 8 years. If after 8 years, continued use of MIRENA is desired, a new MIRENA system should be inserted immediately after the old one is removed. Release rate of Levonorgestrel (LNG) is 21 mcg/day after 24 days; this rate is reduced to about 11 mcg/day after 5 years and 7 mcg/day after 8 years. URL: URL: https://www.allcontraceptives.com/mirena-iud.html https://www.allcontraceptives.com/mirena-iud.html © All Contraceptives

9. Mirena IUD (Levonorgestrel Intrauterine Device) Contraindications Mirena Intrauterine Device is contraindicated in patients with a hypersensitivity to Levonorgestrel or any other component of this medication. The other contraindications are: Pregnancy or suspicion of pregnancy. Cannot be used for post-coital contraception (emergency contraception). Congenital or acquired uterine anomaly if it distorts the uterine cavity. Acute pelvic inflammatory disease (PID) or a history of PID unless there has been a subsequent intrauterine pregnancy Postpartum endometritis or infected abortion in the past 3 months Known or suspected uterine or cervical malignancy URL: URL: https://www.allcontraceptives.com/mirena-iud.html https://www.allcontraceptives.com/mirena-iud.html © All Contraceptives

10. Mirena IUD (Levonorgestrel Intrauterine Device) Contraindications The other contraindications are: Known or suspected breast cancer or other progestin-sensitive cancer Uterine bleeding of unknown etiology Untreated acute cervicitis or vaginitis or other lower genital tract infections Acute liver disease or liver tumor (benign or malignant) Increased susceptibility to pelvic infection A previous intrauterine device (IUD) that has not been removed URL: URL: https://www.allcontraceptives.com/mirena-iud.html https://www.allcontraceptives.com/mirena-iud.html © All Contraceptives

11. Mirena IUD (Levonorgestrel Intrauterine Device) Storage Instructions Mirena IUD (Levonorgestrel Intrauterine Device) have to be stored at controlled room temperature i.e. from 20°C to 25°C (68°F to 77°F) with excursions permitted between 15° to 30°C (59° to 86°F). Keep this as well as all other medicines away from children and pets. URL: URL: https://www.allcontraceptives.com/mirena-iud.html https://www.allcontraceptives.com/mirena-iud.html © All Contraceptives

12. Mirena IUD (Levonorgestrel Intrauterine Device) Warnings Remove Mirena if pregnancy occurs with Mirena in place. If pregnancy occurs, there is increased risk of ectopic pregnancy including loss of fertility, pregnancy loss, septic abortion (including septicemia, shock and death), and premature labor and delivery. Group A streptococcal infection has been reported following insertion of Levonorgestrel Intrauterine System. Strict aseptic technique is essential during insertion. Before using Mirena, consider the risks of Pelvic inflammatory disease (PID). URL: URL: https://www.allcontraceptives.com/mirena-iud.html https://www.allcontraceptives.com/mirena-iud.html © All Contraceptives

13. Mirena IUD (Levonorgestrel Intrauterine Device) Warnings Uterine perforation may occur and may reduce contraceptive effectiveness or require surgery. Risk is increased if inserted in lactating women and may be increased if inserted in women with fixed retroverted uteri or postpartum. Partial or complete expulsion may occur, which can be unnoticed, leading to loss of contraceptive efficacy. Evaluate persistent enlarged ovarian follicles or ovarian cysts. Bleeding patterns become altered, may remain irregular and amenorrhea may ensue. URL: URL: https://www.allcontraceptives.com/mirena-iud.html https://www.allcontraceptives.com/mirena-iud.html © All Contraceptives

14. Mirena IUD (Levonorgestrel Intrauterine Device) Side Effects The most common side effects with an incidence rate of 10% or greater are alterations of menstrual bleeding patterns, abdominal/pelvic pain, amenorrhea, headache/migraine, genital discharge, and vulvovaginitis. URL: URL: https://www.allcontraceptives.com/mirena-iud.html https://www.allcontraceptives.com/mirena-iud.html © All Contraceptives

15. Mirena IUD (Levonorgestrel Intrauterine Device) Overdose An overdose is not likely. The only way to tell, however, is through side effects. URL: URL: https://www.allcontraceptives.com/mirena-iud.html https://www.allcontraceptives.com/mirena-iud.html © All Contraceptives

16. Mirena IUD (Levonorgestrel Intrauterine Device) Mirena IUD During Pregnancy Mirena IUD (Levonorgestrel Intrauterine Device) has been classified by the US FDA as Pregnancy Category X. The use of Mirena during an existing or suspected pregnancy is contraindicated. If the woman becomes pregnant when using Mirena, the system should be removed as soon as possible, since any intrauterine contraceptive left in situ may increase the risk of abortion and preterm labour. Removal of Mirena or probing of the uterus may also result in spontaneous abortion. Ectopic pregnancy should be excluded. URL: URL: https://www.allcontraceptives.com/mirena-iud.html https://www.allcontraceptives.com/mirena-iud.html © All Contraceptives

17. Mirena IUD (Levonorgestrel Intrauterine Device) Mirena IUD During Pregnancy Mirena IUD (Levonorgestrel Intrauterine Device) has been classified by the US FDA as Pregnancy Category X. If the woman wishes to continue the pregnancy and the system cannot be withdrawn, she should be informed about the risks and the possible consequences of premature birth to the infant. The course of such a pregnancy should be closely monitored. The woman should be instructed to report all symptoms that suggest complications of the pregnancy, like cramping abdominal pain with fever. URL: URL: https://www.allcontraceptives.com/mirena-iud.html https://www.allcontraceptives.com/mirena-iud.html © All Contraceptives

18. Mirena IUD (Levonorgestrel Intrauterine Device) Mirena IUD Mirena IUD (Levonorgestrel Intrauterine Device) is manufactured by Bayer, Finland and marketed by Bayer Zydus Pharma Pvt. Limited, India. URL: URL: https://www.allcontraceptives.com/mirena-iud.html https://www.allcontraceptives.com/mirena-iud.html © All Contraceptives