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Molecular Analysis Tools Knowledge Center

Molecular Analysis Tools Knowledge Center. Columbia University and The Broad Institute of MIT and Harvard. Aris Floratos, Columbia University June, 2008. Integrative Cancer Research WS. The primary mission of the Integrative Cancer Research (ICR) Workspace is to

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Molecular Analysis Tools Knowledge Center

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  1. Molecular Analysis Tools Knowledge Center Columbia University and The Broad Institute of MIT and Harvard Aris Floratos, Columbia University June, 2008

  2. Integrative Cancer Research WS • The primary mission of the Integrative Cancer Research (ICR) Workspace is to • Develop and integrate tools to store, link, and analyze diverse data resources in order to enable translational and integrative research, • Engage and grow an adopter community that implements these solutions, and • Foster a collaborative culture to collect, integrate, share, and consume data • ICR supports the bench to bedside continuum for improved diagnostic and prognostic tools and therapies • Provide integrated access to clinical data, genetic data, pathology and laboratory data, proteomic data, population data, clinical outcomes data • The primary mission of the Integrative Cancer Research (ICR) Workspace is to • Develop and integrate tools to store, link, and analyze diverse data resources in order to enable translational and integrative research, • Engage and grow an adopter community that implements these solutions, and • Foster a collaborative culture to collect, integrate, share, and consume data • ICR supports the bench to bedside continuum for improved diagnostic and prognostic tools and therapies • Provide integrated access to clinical data, genetic data, pathology and laboratory data, proteomic data, population data, clinical outcomes data

  3. Supported Tools geWorkbench (http://www.geworkbench.org) • Component-based integrative analysis platform with 70+ components. • Integration of large number of data domains (sequence, expression, literature, network, structure). GenePattern (http://www.genepattern.org) • Modular analysis platform for genomic data with 90+ components. • Powerful scientific workflow framework, web-based. caArray (http://caarray.nci.nih.gov/) • Web and programmatically accessible array data management system. • MIAME compliant. caIntegrator (http://caintegrator-info.nci.nih.gov/) • Novel informatics platform supporting translational informatics. • Integration and aggregation of clinical, genomic, analysis data.

  4. Knowledge Center Mission • End-user support via forums and mailing lists • Maintaining technical and end-user documentation • Collecting, analyzing, communicating to ICR enhancement requests from the user community • Facilitating open-source community development • Dissemination and training • Developing and maintaining informative web presence

  5. Experience • Developers of geWorkbench (Columbia) • Developers of GenePattern (Broad) • Adoption of caArray • Integration of caArray in geWorkbench and GenePattern • Adoption of caIntegrator and programmatic extensions • ICR WS participants and Working Group leaders (Workflow and Analytical Services Best Practices WGs)

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