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Assembling a Systematic Review Team: The Duke Experience

Assembling a Systematic Review Team: The Duke Experience. Gillian D Sanders PhD EPC Director Associate Professor of Medicine Duke Clinical Research Institute Duke University. BCBS Technology Evaluation Center (TEC) Naomi Aronson, PhD Duke University Gillian Sanders PhD ECRI Institute

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Assembling a Systematic Review Team: The Duke Experience

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  1. Assembling a Systematic Review Team:The Duke Experience Gillian D Sanders PhD EPC Director Associate Professor of Medicine Duke Clinical Research Institute Duke University

  2. BCBS Technology Evaluation Center (TEC) Naomi Aronson, PhD Duke University Gillian Sanders PhD ECRI Institute Karen Schoelles, MD, SM Johns Hopkins University Eric B. Bass, MD, MPH McMaster University Parminder Raina, PhD Oregon Health & Science Univ. Mark Helfand, MD, MPH RTI International/ UNC Meera Viswanathan, PhD Southern California RAND Paul Shekelle, MD, PhD Tufts University--NEMC Joseph Lau, MD University of Alberta Terry P. Klassen, MD, MSc Brian H. Rowe, MD, MSc University of Connecticut C. Michael White, PharmD Minnesota Robert L. Kane, M.D. Timothy J. Wilt, MD, MPH University of Ottawa David Moher, PhD Vanderbilt University Katherine Hartman, MD, PhD AHRQ Evidence-based Practice Centers (EPCs)

  3. Duke EPC Project Portfolio

  4. Composition of Project Teams Staff Project Leader Project Coordinator Editor Medical Librarian Investigators (4-8) EPC Oversight Principal Investigator Co-investigators (clinical) Co-investigators (methodological) Statistical investigator

  5. Other Potential Roles Key informants Technical expert panel Peer reviewer

  6. Duke University: EPC Organizational Chart RhaShawn Wells Business Development Associate Juanita Daniels Financial Analyst Gillian D Sanders, PhD EPC Director Rowena J Dolor MD, MHS EPC Associate Director Beverly Perkins, AD Administrative Assistant Connie Schardt, MLS Megan Von Isenburg, MLS Scientific Librarians Project Principal Investigators Amy Kendrick RN, MSN, MS-CRM EPC Manager Rebecca Gray, DPhil Liz Wing, BS, MA EPC Editors Project Co-Investigators Amanda McBroom, PhD Project Leader II Corey Hadley, MM Statistician Brooke Heidenfelder, PhD Project Leader I Karen Pendergast, MPH Project Leader I Julian Irvine, MCM Research Analyst Mike Musty, BA Research Analyst Rachael Posey, MSLS Senior Data Tech Alice Thacher, MBA Research Aide TBD Research Aide

  7. Investigators on Current EPC Projects • Cardiology • Adrian Hernandez • Bimal Shah • Chiara Melloni • Galen Wagner • Jeffrey Washam • Judson Williams • Karen Alexander • Manesh Patel • Matthew Brennan • Monique Anderson • Renato Lopes • Sana Al-Khatib • SreekanthVemulapalli • SumeetSubherwal • William Schuyler • ZubinEapen • Pulmonary • Bill Hargett • Chris Cox • Chris Castillo • Daniel Grilstrap • Joe Govert • NjiraLudugo • General Internal Medicine • Rowena Dolor • Adia Ross • Benjamin Power • David Matchar • Doug McCrory • George Jackson • John Williams • Karen Alexander • Kristine Schmidt • Lori Bastian • Matt Crowley • RaneeChatterjee • Will Yancy • Neurology • Carmelo Graffignino • Dai Wai Olson • Pediatrics • Alex Kemper • Heather VanMater • Family Medicine • David Lobach • Remy Coeytaux • Nursing • Janet PrvuBettger • Kathy Wood • OBGYN/Gyn Oncology • Evan Myers • GeetaSwamy • Laura Havrilesky • Jeff Lowery • Rachel Pergallo • Psychiatry • Marla Wald • Bill Meyers • Biostatistics/HSR/PharmD • Gillian Sanders • AndrzejKosinski • Cindy Green • Gregory Samsa • Jennifer Gierisch • Nancy Allen Lapointe • Trish Moorman • Vic Hasselblad

  8. Managing Conflicts • Make clear up front potential conflicts – financial and intellectual • Delve down in to possible conflicts • Discuss with AHRQ/Task Order Officers • Understand that a conflict on one project doesn’t mean the investigators will be conflicted on all projects • Discuss other potential roles within projects/EPC • Understand incentives for/against participating

  9. Building a Team • Use of fellows, housestaff, junior investigators • Building investigator relationships beyond one project • Having high-level staff to ensure positive EPC experience • Development of methodological abilities in general internists • Working with Division Chiefs to identify investigators • Establishing potential of comparative effectiveness research/systematic reviews as area of research focus • Availability of sustained funding (short term/ long term)

  10. DISCUSSION/QUESTIONS

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