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mmmmm. Infectious Diseases. CHP400 COMMUNITY HEALTH PROGRAM-II. Emerging and Re-emerging Infectious Diseases. Malaria Epidemiology & Control. mmmmm. mmmmm. Mohamed M. B. Alnoor. Malaria. mmmmm. mmmmm. Importance:. mmmmm. 1/2 world pop: live in malarious areas
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mmmmm Infectious Diseases CHP400 COMMUNITY HEALTH PROGRAM-II Emerging and Re-emergingInfectious Diseases Malaria Epidemiology & Control mmmmm mmmmm Mohamed M. B. Alnoor
Malaria mmmmm mmmmm Importance: mmmmm • 1/2 world pop: live in malarious areas • 219 million infections(154 – 289 million), • Kills a child every minute • 660,00 deaths( mostly African children) • 90% deaths in Africa(1/6 childhood deaths) • Untreated P. falicparum < 25% • Anaemia among children • pregnancy :anaemia & low birth weight mmmmm mmmmm
Malaria mmmmm mmmmm Importance: mmmmm • Serious economic impacts in Africa. • A disease of poverty — the poor in malaria-prone rural areas live in poorly-constructed dwellings offering no barriers against mosquitoes. mmmmm mmmmm • Malaria is both preventable and treatable, • Resistance of parasite to drugs • Resistance of mosquito to insecticdes
Malaria mmmmm Mode of Transmission: mmmmm mmmmm Agent: Plasmodium sp. P. falciparum P. vivax P. ovale P. malariae Vector: Anopheline Reservoir: Man mmmmm mmmmm
Malaria mmmmm Mode of Transmission: mmmmm mmmmm Mosquito Man Man Mosquito mmmmm mmmmm 1-3 yrs : P. vivax 1 yr : P. falciparum
Malaria mmmmm Mode of Transmission: mmmmm mmmmm mmmmm mmmmm
Malaria mmmmm Mode of Transmission: mmmmm Factors Influencing Transmission: mmmmm • Host factors • Parasite factors • The vector • The environment mmmmm mmmmm
Malaria mmmmm Immunity: mmmmm mmmmm Unstable malaria: Low endemicity spleen rate ≤ 50% Stable malaria: High endemicity spleen rate ≥ 50% mmmmm mmmmm
Malaria mmmmm Immunity: mmmmm mmmmm Unstable malaria: All population groups Stable malaria: Newborn:3-6/12(immune mothers): childhood: Clinical malaria mmmmm mmmmm • Intermittent absence of parasitaemia. • Lower parasite density. • Premunition. • Splenomegaly.
Malaria mmmmm Immunity: mmmmm mmmmm Stable malaria: Adolescents and adults: Parasitaemia: sometimes Clinical symptoms: occasional Pregnant: especially primigravidae mmmmm mmmmm Immunity Use of prophylaxis: Delays the process of immunity Serious disease on re-exposure
Malaria mmmmm mmmmm mmmmm mmmmm mmmmm
Malaria mmmmm Control (and Prevention): mmmmm mmmmm • Vector Reduction • Vector-host contact reduction • Parasite reduction • Research mmmmm mmmmm
Malaria mmmmm Control (and Prevention): mmmmm mmmmm • Vector Reduction • Breeding sites • Destruction of larvae • Adult anophelines mmmmm mmmmm
Malaria mmmmm Control (and Prevention): mmmmm mmmmm • Vector-host contact reduction • Well screened areas. • Mosquito nets (ITN). • Cover most of the body. • Use repellent on exposed skin. • Insecticide spray. • Antisporozoite vaccine? mmmmm mmmmm
Malaria mmmmm Control (and Prevention): mmmmm mmmmm • Parasite reduction • Chemotherapy • Chemoprophylaxis • Antimerozoite vaccine? • Antigamitocyte vaccine? mmmmm mmmmm • Research
Malaria mmmmm Control (and Prevention): mmmmm mmmmm Roll Back Malaria (RBM) WHO, UNICEF, UNDP and the World Bank, • - ITN • Treatment • Anemia • IPT: mmmmm mmmmm IPTi: 3,6&9- 59% IPTc IPTsc: anemia IPTp: twice
Malaria mmmmm mmmmm mmmmm mmmmm mmmmm
Malaria mmmmm mmmmm Resurgence mmmmm The problem is increasing Vector: Breeding site Cost and resistance Changing habits Parasite: Resistance and cost mmmmm mmmmm
Malaria mmmmm Fansidar 6 years Mefloquine 4 years Atovaquone 6 months mmmmm Resurgence mmmmm Chloroquine 16 years mmmmm mmmmm 1940 1950 1960 1970 1980 1990
Malaria mmmmm mmmmm Resurgence mmmmm • Population: • Movement. • In-cooperation. • Neighboring countries • Inadequate Control: • Political and economic. • Technical. mmmmm mmmmm
Malaria mmmmm mmmmm mmmmm mmmmm mmmmm