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STEP BY STEP MANAGEMENT OF ALTE. Dr. D. Alvarez September 2006. ALTE. An episode that is frightening to the observer and is characterized by some combination of: Apnea Color change Marked change in muscle tone Choking or gagging
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STEP BY STEPMANAGEMENT OF ALTE Dr. D. Alvarez September 2006
ALTE • An episode that is frightening to the observer and is characterized by some combination of: • Apnea • Color change • Marked change in muscle tone • Choking or gagging • In some instant the observer fears that the infant has died. • Recovery occurs only after stimulation or ressuscitation. • Recurrence of ALTE is very frequent and occurs in 30-60% of all ALTE. • True frequency of recurrence is probably even higher since many true documented apnea not leading to full blown ALTE go undetected by parents.
ALTE – Definition (Other) • Episode frightening to the observer plus 1 or more of the following • Apnea central > obstructive • Color changes: blue or pale • Sudden limpness) • Chocking – gagging • Recurrence 13 %
INITIAL PROCES • Call from the ED/4-B requesting bed for a patient with Diagnosis of ALTE • Resident / Supervisor (if applicable) obtains information on patients condition, on the phone or going to the ED/4-B, (as activity in the unit warrants). • Information needed: • Detail history from the observer (who was with the infant during the “episode”)
ALTE - History should include • Duration of the event • Time of the day • Time after feeding (any changes in feeding if any) • Adequacy of lighting • Infant position within his / her surroundings (soft bedding, pillows?) • Did episode began while awake or asleep • Changes in Color • Changes in muscle tone • Need for any type of resuscitation (describe) • Was any blood or pink frothing coming from infants mouth or nose • Appropriateness of caregiver’s concerns • Fly. Hx of SIDS or serious illness with coma • Any associated respiratory symptoms.(URI – Coughs)
Focus PE (ALTE) • Alertness • Tone • Bruising • Scalp swelling • Disuse of extremities • Fundoscopy, retinal hemorrhages • Chest exam, stridor.
Selected Causes of ALTE • RSV, Pertusis • Sepsis with apnea • Syndromes compromising the upper airway (Pierre-Robin) • Breath holding spells • Seizures • Intracraneal hemorrhages, vascular abnormalities, child abuse, Vit K deficiency. • Exaggerated laryngeal chemoreceptor with or without GER • Drug. (Phenothyazede) • Tachyarreithmias, SVT, prolongued QT intervale. • Inborn errors of metabolism • Hypoventilation during bed sharing.,soft bedding
Apnea of Infancy • An ALTE episode with no found cause. • Unexplained episode of cessation of breathing for > 20 sec, or shorter respiratory pause associataed with bradycardia, cyanosis, pallor, and/or marked hypotonia in an infant whose age during initial event is > 37 wks postconceptional age.
ED Events. 4.- Review of ED-Events • Assessment on presentation to ED • Intervention / therapies and response • Studies / labs done (Start laboratory flow sheets record) • CBC with diff and • Electrolytes. • Look for hypoglycemia, metabolic acidosis. • Source of infection: UA, blood cultures. • CxR Look for any lung pathology and heart side • EKG 5.- Communicate with PICU Attending and inform on patient’s condition. 6.- Inform PICU Nurses that patient was accepted and up-date them on patient’s condition.
GENERAL / OVERALL ASSESSMENT AND FOCAL FINDINGS Identify/investigate and treat focal abnormalities such as: • Possible bacterial infection early sepsis? • Respiratoy symptoms • Close respiratory monitoring • CxR • Respiratory therapy according to pathology: URI?, LRI • Cardiovascular abnormalitis • Cardiomegaly, EKG abnormalities • Continue investigations according to physical exam • R/O CNS infections >LP ? Head CT • Metabolic screening: ABG, Lactic Acid, LFT, ammonia level
Basic Recommended Evaluation for ALTE • Admit to observation and cardiorespiratory monitoring • Careful history, physical and neurologic examination • Complete blood count • Blood glucose, electrolytes, Calcium • CxR, ECG, • Arterial Blood gases • EEG • Multichannel recording including oxygenation.
Evaluation of ALTE in Selected Cases: • Septic workup (blood, urine, CSF cultures) • Barium Swallow • Lateral neck x Rays • Milk scan • PH probe • U/S or CT scan of brain • Echocardiogram • Blood amonia and urine Amino acid if recurrent.
“Indication” for home C-R monitoring • History of ALTE • Multichanel documentation of clinical significant Apnea • Twin of SIDS • Apnea of Prematurity • Periodic breathing associadited with hypoxia • Feeding associated with apnea and bradycardia • Technology dependent children • ISAM (Selected cases) • Sibling of SIDS (Selected Cases)
Home Monitor Settings: • Heart Rate Alarm • High: 220 bpm • Low: • 70 bpm (< 2 mo) • 60 bpm (2-8 mo) • 50 bpm (> 8 mo) • Apnea: • > 15 sec – record • > 20 sec – alarm • If SaO2 is monitored: Alarm set at < 85 %
ALTE Begin Monitor 2-3 months no true alarms Event Record Normal Abnormal Event Recording True Alarms Continue Monitoring Discontinue Monitor