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Objectives. Explain what is meant by the term endocrine gland . Describe the cellular structure of an islet of Langerhans from the pancreas. Outline the role of the pancreas as an endocrine gland. `. http://www-medlib.med.utah.edu/WebPath/ENDOHTML/ENDO032.html. Pancreas.
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Objectives • Explain what is meant by the term endocrine gland. • Describe the cellular structure of an islet of Langerhans from the pancreas. • Outline the role of the pancreas as an endocrine gland.
` http://www-medlib.med.utah.edu/WebPath/ENDOHTML/ENDO032.html
Pancreas • Exocrine Gland: a gland that secretes externally through a duct • Endocrine Gland: a gland that secretes hormones into the bloodstream.
Pancreas • The pancreas has an exocrine portion that secretes digestive enzymes that are carried through a duct to the duodenum. The endocrine portion consists of the pancreatic islets, which secrete glucagons and insulin.
Objectives • Explain how the blood glucose concentration is regulated by negative feedback control mechanisms, with reference to insulin and glucagon. • Discuss the importance of homeostasis in mammals, and explain the principles of homeostasis in terms of receptors, effectors and negative feedback.
Hormones • Most hormones circulate in blood, coming into contact with essentially all cells. However, a given hormone usually affects only a limited number of cells, which are calledtarget cells. A target cell responds to a hormone because it bears receptors for the hormone. • The effector is usually an organ.
Objectives • Explain the advantages of treating diabetics with human insulin produced by genetic engineering.
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