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Environmental Medicine. Dr shabeel pn. Environmental Medicine. One’s sensitization to their environment Exposure does not lead to consistent symptoms Randomization of symptoms can confuse the practitioner Drug prescription can add to the problem. The Cause of Disease. Genetic
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Environmental Medicine Dr shabeel pn
Environmental Medicine • One’s sensitization to their environment • Exposure does not lead to consistent symptoms • Randomization of symptoms can confuse the practitioner • Drug prescription can add to the problem
The Cause of Disease • Genetic • Psychogenesis • Environmental • Nutrient Deficiency
Food Induced Disease • Arthritis • Stay away from vegetables in Nightshade category • Prescribe NSAIDs lead to LGS • Celiac Disease • Wheat intolerance • MSG • Retinal degeneration • Milk induced hypochlorhydria • Leads to nutrient deficiency
Illness Induced by Chemicals • Plasticizers TMA (trimellitic anhydride)…complex antigens • Dry Cleaning Fluids…CVS • Solvents..panic disorders • Hydrocarbons...glomerulonephritis • Formaldehyde..fatigue-cancer • Pesticides..brain fog (loss concentration, poor memory, irritability, depression)
Chemicals Everywhere • Chemical exposure is ubiquitous and ever increasing • Sources other than work and environment • Bedroom – Fabric softeners, flame retardants, dry cleaning chemicals • Bathroom – chlorine, cosmetics, shampoos, toothpaste, hair products, colognes, and the like • Kitchen – pesticides, hormones, antibiotics, cookware, plastics, petroleum residues, trans fats, flavorings, sweeteners
Chemical Illness • Free Radicals • Phase I detoxification • Highly reactive and destructive • Will rip the electron from anything in its path…cell enzymes and cell membrane • Membranes attacked • Dictates what goes on in the cell • Regulate calcium channels • Regulate sodium pump • Provide access to genetic material • Where endoplasmic reticulum exists
Chemical Sensitivity • Information • does not alert the practitioner • live with chronic conditions • Frustrated • symptoms are compounded by other symptoms • Sick Building Syndrome • Chronic Fatigue Syndrome • Work efficiency plummets
Suspicion • WHY IS EVERYONE NOT AFFECTED EQUALLY? • Depends On: • Genetics • Sensitization: • How much of what?
Unexpected Death • The body is equipped with detox mechanisms • The detox mechanisms do fail • Upon failure disease occurs • Drugs can contribute to failure • Proteins and enzymes break down • Leads to tissue death • Leads to over all death
7 Principles of Environ Medicine • 1. Biochemical individuality • 2. Total load • 3. Spreading phenomenon • 4. Adaptation • 5. De-adaptation • 6. Bi-polarity • 7. Switch phenomenon
Total Load • Conjugates (sulfur containing compounds that facilitate removal of xenobiotics) • Genetic predisposition • e.g. brown eyed individuals are mineral deficient • In turn enzymes are not functional in purported activity
3rd Principle • Spreading phenomenon • Patients are reactive to xenobiotics that never before bothered them. • Doctors unfamiliar with chemistry of detoxification begin: • To doubt patient motives • Sanity of the individual • The allopathic paradigm • Suppress symptoms with drugs • Chronic use of drugs no longer effective • Recommend surgery
4th Principle • ADAPTATION • Chronic Disease • The sick get sicker • Body mechanism • More load…more need of enzymes • Enzyme induction • Non-sedative antihistamines • Enzyme induction leads to neoplasm
5th Principle • De-Adaptation • Phenol exposure • Preservative in medicines • Found in home office furnishing and cleaners • Picked up readily by the body • Overwhelms enzyme network for removal • Shifted to other pathways where not completely metabolized
6th Principle • Bipolarity • Same agent can cause opposite effects • e.g. alcohol • Initially it is stimulatory • Once the aldehyde is produced it causes the body to become depressed • Outcome depends on: • Dose • Time frame • Adaptive enzymes
7th Principle • Switch Phenomenon • Target organ switches from one to another • e.g. asthmatic person with cardiac abnormalities, or IBS • One disease is active while the other is quiescent and visa versa • Secondary importance are the symptoms • Primary importance is to find cause
Drug Complications • Environmental Medicine • Drugs contribute to symptoms • Cumulative biochemical effect • Cause nutrient deficiencies • Diuretics cause hypokalemia and magnesium deficiency • Both deficiencies lead to hypertension • Mg deficiency leads to lipidemia and reduction of delta-6-desaturase • D-6D is crucial in fatty acid metabolism; damage endoplasmic reticulum where detoxification takes place • Spreading Phenomenon
Complications • What about hobbies, chemical applications in the home, exposures during traffic, etc.? • Needless to say a plethora of minutia needs to be sifted through if one is to uncover the cause • Uncover the cause • Reverse the symptoms
Physical Signs • Common findings not reported: • White fury tongue • Dark spots under the eyes • White, splitting nails • Swelling • Skin temperature • Tooth loss, amalgams, mixed oral metals • Body odor • Abnormal eye movements • Poor focusing, memory • Inability to stand on one leg or tip toes with eyes closed (common malfunction due to pesticide exposure).
Reversal • Bowel studies are necessary • Rule out unsuspected inflammation • Malabsorption with insufficient break down of protein • Abnormal flora • Insufficient beneficial flora • Bowel flora play role in metabolizing vitamins, drugs, hormones, carcinogens, and xenobiotics.
Patient Education • Through knowledge we are now able to recommend: • Remove smelly plastic mattress covers • Foam pillows • Water beds • Air cleaners with particle board cabinets • Furnishings that out-gas phenol and formaldehyde
Physician Awareness • Minimize the use of drugs to treat symptoms • e.g. use of NSAIDs for osteoarthritis • Can actually lead to rheumatoid conditions • Arthritics are to abstain from red meat and vegetables in nightshade category • Potatoes, tomatoes, peppers, eggplant, chili, paprika • Also, abstain from tobacco
Physician Awareness • Common causes of fatigue and depression…eating foods under the ferment category: • Bread, cheese, vinegar, catsup, mustard, mayonnaise, salad dressing, alcohol, chocolate, anything aged, pickled, or fermented
New Medical paradigm • Include environmental toxins • Correct the cause rather than the symptom • Remove food intolerances • Laboratory analysis of the bowel and intracellular Zn, Se, Mo, Cr, Mn, K, Cu, and folate • Recalcitrant conditions may be from amino acid deficiency