Figure 2

1. Caenorhabditis RME-2 Dermacentor VgR Penaeus OLR 98 Solenopsis VgR Leucophaea VgR 100 99 97 Blattella VgR Insect VgR Periplaneta VgR 75 Tribolium XP_968903.1 Drosophila VgR 54 100 Anopheles VgR Aedes VgR 50 Gallus megalin 100 Megalin Bos LRP2 megalin 100 100 Apis XP_393369 82 Megalin-like Drosophila EAL32723 Caenorhabditis LRP 100 Canis LRP1 100 LRP1 Mus LRP1 Gallus LRP1 89 Apis LpR Tribolium XP_967944.1 91 97 Leucophaea LpR 100 Blattella LpR 66 99 Locusta LpR LpR Bombyx LpR 100 98 55 Galleria LpR 96 Drosophila LpR Glossina LpR Aedes LpR 99 Anopheles XP_307995 Mus LDLR 100 Rattus LDLR 51 89 Cricetulus LDLR 100 Sus LDLR 100 Bos LDLR LDLR 73 Homo LDLR 74 Oryctolagus LDLR 79 Xenopus LDLR 93 Chiloscilium LDLR 98 Tetraodon CAF92585.1 100 Bos LDLR-LRP8 LRP8 Gallus LRP8 Oncorhynchus VgR 92 100 55 Anguilla VgR Conger VgR 96 54 Morone VgR Oreochromis VgR 100 100 Danio VLDLR Xenopus VgR 97 Vertebrate VgR-VLDLR Gallus VgR Rattus VLDLR Mus VLDLR 55 Macaca VLDLR 100 Homo VLDLR Pan VLDLR Bos VLDLR Canis VLDLR Oryctolagus VLDLR 0.2 Figure 2