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1. Guideline for hypertension
3. Etiology Essential (90%)
Renal : renal artery stenosis ; parenchymal disease
Endocrine : Pheochromocytoma ; Hyperaldosteronism ;
Cushing syndrome ; hyperthyroidism
Exogenous agent
Coarctation of aorta :
Toxemia of pregnancy
4. Standard work-up Conformation of real hypertension
Identify Etiology of H/T
Access of End-organ damage
Identify cardiovascular risk
5. How to record BP Measure BP several times on several occasions with the patient in sitting position . including Self Measurement
Use a mercury sphygmomanometer or other
non-invasive device .including Ambulatory BP monitorings
7. History Onset of hypertension; Drug history; Family History; Other major cardiovascular risk factors; major target organ complications; Exogenous agents
(e.g. oral pills, Licorice)
8. History Hisory of flank pain, hematuria, history of renal trauma ->
Renovascular hyprertension;
Histoy of proteinuria, pyelitis of pregnancy, renal stones, dysuria, fever, or chill -> Parenchymal renal disease as a cause of hypertension;
History of headache, sweating, palpitations, tachycardia, thoracic and epigastric distress, and weight loss …. Pheochromocytoma;
Heat intolence and loss of weight …… Hyperthyroidism,
History of weakness, paralysis, tetany, paresthesia, polyuria… primary aldosteronism.
9. Physical Examination General apperance : eg .Cushing syndrome
Serial blood pressure determinations
Blood pressure in both arms
Funduscopic examination :arteriovenous nicking , hemorrhage, Exudates
Palpation of thyroid
Auscultation
Lungs for wheezing and rales
Cardiac: heart beat; S3 ,S4 murmur , PMI , thrill ….
Abdominal and cervical ( check bruit )
Palpation of pulses, especially femoral artery :delayed pulse and decrease pressure -> coarctation
10. Laboratory test Routine screen ,including CBC/DC ,biochemistry and admission panel
Urinalysis : including specific gravity , albumin , microanalysis
Serum potassium , Calcium ,Creatinine
Thyroid function , Cortisol level
Chlesterol , TG
EKG
Chest X-Ray
Catecholamines only in presence of diastolic pressure >110 mmHg in patient younger than 30
Echocardiography
11. Risk factor for Cardiovascular disease Levels of systolic and diastolic blood pressure (Grades 1-3)
Men > 55 years
Women > 65 years
Smoking
Total cholesterol > 6.5 mmol / L ( 250 mg / dl)
Diabetes
Family history of premature cardiovascular disease
Homocystine
12. End –Organ damage Left ventricular hypertrophy
( electrocardiogram, echocardiogram or radiogram )
Proteinuria and/or slight elevation of Left ventricular hypertrophy plasma creatinine concentration (1.2-2.0 mg/dl)
Ultrasound or radiological evidence of atherosclerotic plaque (carotid, iliac and femoral arteries, aorta)
Generalized or focal narrowing of the retinal arteries