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Drugs and the Nervous System

Drugs and the Nervous System. Addiction and alterations of NT actions. Is it a disease or a Choice? Is there a cure or a Change?. 2007 National Survey on Drug Use and Health: National Findings Substance Abuse and Mental Health Services Administration. Injection Inhalation Ingestion

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Drugs and the Nervous System

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  1. Drugs and the Nervous System Addiction and alterations of NT actions

  2. Is it a disease or a Choice? • Is there a cure or a Change?

  3. 2007 National Survey on Drug Use and Health: National FindingsSubstance Abuse and Mental Health Services Administration

  4. Injection Inhalation Ingestion Shorting Methods for taking Drugs?

  5. Who will experience greatest effect? Who will experience least effect? Who will experience quickest effect? Who will experience slowest effect? What factors can change effects of drugs on your body? Analyze the Graph

  6. Why can’t you get addicted to all types of drugs? • Drugs that alter only neurotransmitters levels • Genetic probability

  7. Bind to receptors and increase action of NT Mimic action of NT Nicotine: acH Increase level of NT Ex: nicotine Cause NT to remain in synaptic cleft Ex: cocaine Blocks reuptake LSD blocks serotonin How drugs work

  8. Agonists Activates the receptor triggering an action potential or helps NT bind Antagonists Binds to a receptor preventing a NT from binding there Types of Drugs

  9. Why addiction occurs? • When taking drugs they either bind to a receptor or enhance NT action. • The number of receptors that the NT/drug binds can decline….This can lead to? • Needing more of the drug to get the same effect

  10. DRUGS: altering NT actions • Cocaine: blocks dopamine reuptake • Effect: euphoria • Happiness, increases energy

  11. Tryptophan: increases serotonin • Precursor to serotonin • Dietary sleep aid • Sleepiness

  12. Drugs that alter NT levels • Valium: GABA (enhances some receptor enhances receptor binding) • Decreases anxiety • aka gamma aminobutyric acid • Nicotine: increases receptors of AcH • mimics AcH • Pleasure/ alertness • Dopomine

  13. http://learn.genetics.utah.edu/content/addiction/drugs/mouse.htmlhttp://learn.genetics.utah.edu/content/addiction/drugs/mouse.html

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