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Human Karyotype- (Diploid= 2n)

Human Karyotype- (Diploid= 2n). Normal human- how many homologous pairs? What is the sex? How many chromosomes does each parent contribute?. What if chromosomes fail to separate properly?. Nondisjunction Failure of chromosomes to separate properly during meiosis.

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Human Karyotype- (Diploid= 2n)

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  1. Human Karyotype- (Diploid= 2n) • Normal human- how many homologous pairs? • What is the sex? • How many chromosomes does each parent contribute?

  2. What if chromosomes fail to separate properly?

  3. NondisjunctionFailure of chromosomes to separate properly during meiosis

  4. Abnormal Gametes result in abnormal diploid condition SOMATIC TRISOMIES Down Syndrome Trisomy 13- cleft palate, eye brain circulatory defects Trisomy 18- death in months Trisomy 16-death in months SEX CHROMOSOMES TRISOMIES Turner Syndrome-X0- only viable monosomy in humans, Never mature sexually Klinefelter Syndrome XXY XYY- Super male- aggression XXYY NOTE: the role of the Y chromosome…its presence yields malesness- otherwise default to female

  5. Cancer Cell Karyotype

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