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1 Thailand MOPH-US CDC Collaboration, Nonthaburi , Thailand

Prevalence of Chlamydia trachomatis and Neisseria gonorrhea infection by anatomic site in a cohort study of men who have sex with men (MSM) in Bangkok, Thailand.

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1 Thailand MOPH-US CDC Collaboration, Nonthaburi , Thailand

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  1. Prevalence of Chlamydia trachomatis and Neisseria gonorrhea infection by anatomic site in a cohort study of men who have sex with men (MSM) in Bangkok, Thailand W. Chonwattana1, J. Tongtoyai1, C.S. Todd1,2,3, S. Pattanasin1, S. Chaikummao1, P. Wasinrapee1, A. Varangrat1, S. Lokpichart4, T. Holtz1,5, A. Chitwarakorn6, M. Curlin1,5 1Thailand MOPH-US CDC Collaboration, Nonthaburi, Thailand 2FHI360 - Asia Pacific Regional Office, Bangkok, Thailand 3AVRAM Corporation, Miami, United States 4Thai Bureau of AIDS, TB and STD, Department of Disease Control, MOPH, Bangkok, Thailand 5Division of HIV/AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, United States, 6Thailand Ministry of Public Health, Nonthaburi, Thailand

  2. Background • Chlamydia trachomatis (CT) and Neisseria gonorrhea (NG) are among the most prevalent bacterial sexually transmitted infections (STIs) • Men who have sex with men (MSM) are at increased risk of acquiring these infections through high-risk sexual practices • The CDC recommends routine screening sexually active MSM for urethral and rectal CT/NG, and for pharyngeal NG • Prevalence of CT and NG by anatomic site were examined to assess the disease burden and need for prevention • Thai, male at birth, ≥ 18, had history of insertive or receptive sex with other man • Infections determined by NAAT or culture • Symptomatic cases defined during clinical assessment

  3. Results • Among 346 infected individuals, only 8.3% (29/346) were symptomatic • Among men with rectal symptoms, infection was most often due to CT, 71.4% (5/7) • Among men with urethral symptoms, infection was more likely to be due to NG infection, 86.3% (19/22)

  4. Discussions • Prevalence of pharyngeal NG in this study might be underestimated due to the low sensitivity of culture • Evaluation for pharyngeal CT in individuals who engage in sexual practices involving this site, should also be considered • Routine screening of asymptomatic persons at high risk of STIs may interrupt further transmission of CT and NG infections as well as prevent the transmission of other STIs including HIV

  5. Acknowledgments • MSM Volunteer in the cohort • Division of HIV/AIDS Prevention, US CDC • Bureau of AIDS, TB and STI, Thailand MOPH • MSM-Community Advisory Board • Silom Community Clinic and support staff • HIV/STD Laboratory staff

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