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EPIDEMIOLOGY. What is Epidemiology?. Distribution of Disease WHEN Time WHERE Place WHO Person. EPIDEMIOLOGY. Distribution of Disease. Time Changing or stable Cyclic Seasonal secular. EPIDEMIOLOGY. Distribution of Disease. Place Geographic
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EPIDEMIOLOGY What is Epidemiology? Distributionof Disease WHEN Time WHERE Place WHO Person
EPIDEMIOLOGY Distribution of Disease • Time • Changing or stable • Cyclic • Seasonal • secular
EPIDEMIOLOGY Distribution of Disease Place Geographic -Restricted/Wide spread -Coastal/inland Weather(temp. , humidity , rainfall) Altitude/latitude/longitude Urban/rural
EPIDEMIOLOGY Distribution of Disease • Person • Age • Sex • Race • Education • Occupation • behavior
EPIDEMIOLOGY Distribution of Disease morbidity rates Incidence rate • The numerator is newcases • The denominator may change over time as people develop disease • However, in practice • in large studies, the denominator is often the mid- year population • in small studies, the denominator includes persons at risk of the disease
EPIDEMIOLOGY Distribution of Disease morbidity rates Attack rate عليه مسائل Number of episodes during specified period x 10n Attack rate = Population at risk/ period • Acute recurrent diseases , • e.g. URTI, food poisoning. • A person may catch the disease more than once.
EPIDEMIOLOGY Distribution of Disease morbidity rates Attack rate Example: In a village of 600 persons, 120 visits to the PHCC were due to food poisoning. What is the attack rate of food poisoning in the village ?
EPIDEMIOLOGY Distribution of Disease morbidity rates Attack rate Example: In a village of 600 persons, 120 visits to the PHCC were due to flu. 0 What is the attack rate of flu in the village ?
EPIDEMIOLOGY Distribution of Disease morbidity rates Incidence rate Factors affecting incidence: 1- New risk factor Contraceptive pills & thromboembolism. 2- Changing virulence H1N1virus & influenza pandemic 3- Changing pattern of intervention Chemoprophylaxis & meningitis
EPIDEMIOLOGY Distribution of Disease morbidity rates Incidence rate Factors affecting incidence: 4-Population pattern Aging & degenerative diseases & cancer 5- Reporting incidence Increase in reporting & Early stage of surveillance & incidence
EPIDEMIOLOGY Distribution of Disease morbidity rates Incidence rate Factors affecting incidence: 6-Screening 7-New diagnostics Screening New diagnostic early detection of cases detection of cases incidence incidence
EPIDEMIOLOGY Distribution of Disease morbidity rates Incidence rate Factors affecting incidence: 8- Changing classification Blood pressure 140/80 mmhgVs 160/90 mmhg incidence Fasting blood sugar 126 mg/100ml Vs 140 mg/100ml incidence
EPIDEMIOLOGY Distribution of Disease morbidity rates Prevalence rate مسائل وتفهمي ايش يعني • Point prevalence • Period prevalence • It involves old and new cases • It measures the disease status in the population. • It measures the disease burden. ( All Cases)
EPIDEMIOLOGY Distribution of Disease morbidity rates Prevalence rate Point prevalence: Total cases (old + new) at fixed point of time in a place X = 1On total population in that place
EPIDEMIOLOGY Distribution of Disease morbidity rates Prevalence rate Period prevalence: Total cases (old + new) during a period of time in a place X = 1On total population in that place
EPIDEMIOLOGY Distribution of Disease morbidity rates prevalence rate example MOH conducted a survey for RVF among workers in slaughterhouses in Makkah . 224 seropositive workers were identified among 6000 workers. Calculate the prevalence of RVF.
EPIDEMIOLOGY Distribution of Disease morbidity rates prevalence rate Factors affecting prevalence : 1- Incidence rate & 2- Disease duration average duration of disease Prevalence rate Incidence rate X = Incidence Prevalence Prevalence Longer duration