Reproductive system

1. Reproductive system

2. Male reproductive system. • Female reproductive system.

3. testis • Genital excurrent ducts • Accessory sex glands • penis

4. Ductus epididymis Efferent ductule Rete testis Straight tubule Seminiferous tubule bladder prostate Seminal vesicle Bulbourethral gland Ductus deferens Corpus spongiosum Corpus cavernosum epididymis testis Tunica vaginalis

5. 一、testis • summary • tunica albuginea→septum • lobules of testis • in each lobule, consist of seminiferous tubules. • CT stroma , contains interstitial cells .

6. Testis& epididymis

7. （一）seminiferous tubule • seminiferous epithelium • Supporting cells/ sertoli cells • Spermatogenic cells

8. Seminiferous tubule

9. Basal lamina spermatogonium Primary spermatocyte Sertoli C spermatid

10. 1.Spermatogenic cells • spermatogonium • primary spermatocyte • secondary spermatocyte • spermatid • spermatozoa spermatogenesis

11. （1）spermatogonium • location: closely attach to basal lamina of spermatogenic Epi. • round，organells poorly-developed • differentiate into primary spermatocyte

12. A型 B型

13. spermatogonia

14. （2）primary spermatocyte • attach to the luminal surface of the spermatogonia. • large. • after 1 st meiotic division，produce 2 secondary spermatocyte。

15. Primary spermatocytes

16. （3）secondary spermatocyte • Not easy to be seen in section. • After the second meiotic division，form 2 spermatids.

17. （4）spermatid • adjoining to the lumen. • No division，undergo extensive cell remodeling , as they differentiate into sperm. • this process is called spermiogenesis。

18. （5）sperm • Shaped pollywog，divide into head sperm & tail sperm。 • head: nucleus+acrosome。 • In acrosome, variant acrosomal enzymes. • tail: motile equipment .

19. sperm

20. sperm

21. 2. supporting C • Sertoli C. • stained lightly，nucleulus is obvious。 • sides with tightly junction. • support , nutrient spermatogenic cells.

22. Supporting C

23. Blood-seminiferous tubule barrier： • The structure , prevent large molecular substances exchange between the blood and the seminiferous tubule. • costituents：endothelium & basal lamina of cap. 、CT、basal lamina of spermatogenic epi. And the tight junctions of adjoining supporting C . • Tight - junction is the essential constituent of blood-seminiferous tubule barrier.

24. （二）interstitial C • Leydig C, In group, large , polygonal, highly eosinophilic . • Steroid-secreting C: elaborate sER, Mit. With cristae. Secret testosterone/androgen

25. Interstitial C

26. Functions of leydig C • maintain spermatogenesis & secondary sex characteristics. • Be responsible for the development of genital organs in male. • Keep sex capability.

27. （三）straight tubule & rete testis • Straight tubule: near the mediastinum of the testis ,where seminiferous tubule assume a short straight course. • Rete testis: the straight tubule empty into the rete testis, an anastomosing channel system within the mediastinum. • Sperm produced in seminiferous tubule pass by straight tubule & rete testis , leaving testis and arriving in epididymis .

28. Straight tubule Rete testis seminiferous tubule

29. 二、epididymis summary • head、body & tail. • head: efferent ductules. • body & tail: dutus epididymis.

30. 1.efferent ductules • 8-12，continuous with rete testis • Epi.=high columnar C+low columnar C • Lumen is irregular • cilia is present.

32. efferent ductules

33. 2.dutus epididymis • 4-6m，highly convoluted • pseudostratified ciliated columnar Epi.=principal C + basal C • lumen is regular，filled with sperm & secretions • the proximal , efferent ductules; the distal, ductus deferens.

34. dutus epididymis

35. Epi. dutus epididymis

36. 三ductus deferens • mucosa+muscular wall + adventitia • pseudostratified ciliated columnar Epi.=principal C + basal Cinner • muscular wall :longitudinal,middle circular, outer longitudinal SMC

37. Ductus deferens

38. Ductus deferens

39. thank you!