Glucocorticoids

Feb 05, 2013

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Adrenal steroids. zona glomerulosamineralocorticoids (water

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Glucocorticoids

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Mixing Glucocorticoids WITH DIABETES

By: Tamara R Meier, MS, APRN, CCNS. Mixing Glucocorticoids WITH DIABETES. OBJECTIVES. Analyze medications used to treat diabetes mellitus Determine therapy for treatment of glucocorticoid induced hyperglycemia Develop treatment plan for diabetics requiring glucocorticoid therapy.

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Visiting Scholar Series The Role of Endogenous Glucocorticoids in Bone Remodeling

College of Dentistry DOWS Institute. Maobin Yang, DDS, PhD Division of Endodontology , School of Dental Medicine University of Connecticut Health Center Farmington, CT. Visiting Scholar Series The Role of Endogenous Glucocorticoids in Bone Remodeling. 14B Galagan DSB

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Glucocorticoids-2

Glucocorticoids-2. Dr. Alia Shatanawi 26-2-2013. Chronic Primary Adrenocortical Insufficiency ( Addison’s Disease ) D efficiency in corticosteroid production

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Glucocorticoids

Glucocorticoids. High levels of circulating cortisol, as seen with corticosteroid drugs (prednisone), or tumors (adrenal cortex, pituitary gland) is called Cushing’s syndrome Manifestations include hyperglycemia, poor wound healing, osteoporosis, dermatitis, fat

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Glucocorticoids

Glucocorticoids. Dr. Alia Shatanawi 24-2-2013. Introduction. Adrenal gland: Cortex and Medulla Adrenal cortex: 3-layer Outer: zona glomerulosa: Middle: zona fasciculata Inner: zona reticularis. Corticosteriods Mineralocorticosteriods (Aldosterone)

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Adrenal Steroids Mineralocorticoids & Glucocorticoids

Adrenal Steroids Mineralocorticoids & Glucocorticoids. Adrenal Gland Cortex Mineralocorticoids (Aldosterone)

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STRESS, GLUCOCORTICOIDS, AND YOUR BRAIN

STRESS, GLUCOCORTICOIDS, AND YOUR BRAIN. Stress Hormones: Glucocorticoids. Cortisol in the human Corticosterone in the rat Secreted by the cortex of the adrenal gland. Landfield et al .(1979,1981). Basal (resting) levels of glucocorticoids ( GCs ) rise with age in rats

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Clinical Doses Glucocorticoids

Clinical Doses Glucocorticoids. Inflammatory 0.25– 0.5 mg/kg q.12 h (dog), 1–2 mg/kg q.12 h (cat) Immune-mediated (autoimmune ) eg : IMHA and Thrombocytopenia, Immune-mediated polyarthristis , IBD 1.0–2.0 mg/kg q.12 h (dog), 2.2–6.6 mg/kg q.12 h (cat) Acute spinal cord injury

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GLUCOCORTICOIDS AND MINERALOCORTICOIDS

GLUCOCORTICOIDS AND MINERALOCORTICOIDS. Corticosteroids. Adrenal glands produce glucocorticoids and mineralocorticoids Glucocorticoids: Involved in cholesterol, fat, and protein metabolism. Corticosteroids. Adrenal glands produce glucocorticoids and mineralocorticoids Glucocorticoids:

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Antenatal Glucocorticoids and BPD

Antenatal Glucocorticoids and BPD. Evidence based interventions and BPD Postgraduate Course in Neonatology Lausanne, February 28, 2002 Thomas M. Berger NeoIPS, Kinderspital Luzern. Antenatal Glucocorticoids and BPD Overview. Antenatal Glucocorticoids and BPD Small Bowel Phosphatase.

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Lightman, S. L. & George, C. L. (2013) Glucocorticoids—timing, binding and environment

Figure 1 ER and GR bind to specific DNA binding sites to regulate the expression of their target genes (arrows indicate transcription). Lightman, S. L. & George, C. L. (2013) Glucocorticoids—timing, binding and environment Nat. Rev. Endocrinol. doi:10.1038/nrendo.2013.257.

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Regulation of Stress Induced Cytokine Response by Glucocorticoids

Regulation of Stress Induced Cytokine Response by Glucocorticoids. Janine Gilkes Biology 520 2/11/09. HPA axis Activation Induced by Stressors. Stress illicits an immune response resulting in bi-directional signaling between the immune and central nervous system (CNS)

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Clinical use of glucocorticoids

Clinical use of glucocorticoids. Abi Karam Ghada. Pathophysiology and management of glucocorticoid induced osteoporosis. Bianchi, Genoa, Italy.

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Glucocorticoids And Their Effects On The Innate Immune System Of The CNS

Glucocorticoids And Their Effects On The Innate Immune System Of The CNS. Kevin Taliaferro Bio 520 Presentation Feb 25, 2009. Glucocorticoids: The HPA axis. (Glezer, 2004). Inflammatory Signaling in Microglia. (Glezer, 2004). Chronic inflammation and Neurodegeneration. (Block, 2007).

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Stress-dependent Glucocorticoids and Proinflammatory Cytokines Impair Wound Healing

Stress-dependent Glucocorticoids and Proinflammatory Cytokines Impair Wound Healing. Carla Cueva Biol 520 March 11 th , 2009. Outline. Introduction Hypothesis Experimental findings Summary Conclusions Take home message Future experiments References. What is Stress?.

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Corticosteroids / Glucocorticoids

Corticosteroids / Glucocorticoids. Endocrine and Non-Endocrine Uses. Specific Drugs. Prednisone (Deltasone) Methylprednisolone (Solumedrol IM/IV) Cortisone Betamethasone (Diprolene) Dexamethasone (Decadron) Hydrocortisone (Solucortef IM/IV) Prednisolone

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Glucocorticoids maintain human osteoclasts in the active mode of their resorption cycle

Glucocorticoids maintain human osteoclasts in the active mode of their resorption cycle. Osteoscoop - Issue N°159 – November 2010. CONTROL. ON. OFF. OFF. ON. Osteoclasts. Time. CONTROL. ON. OFF. OFF. ON. Osteoclasts. GLUCOCORTICOID. OFF. ON. ON. ON. Time.

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Adrenal Steroids Mineralocorticoids & Glucocorticoids

Adrenal Steroids Mineralocorticoids & Glucocorticoids. Munir Gharaibeh, MD, PhD, MHPE Faculty of Medicine The Jordan University April 2014. Adrenal Gland Cortex Mineralocorticoids

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Presentation Transcript

Mixing Glucocorticoids WITH DIABETES

Visiting Scholar Series The Role of Endogenous Glucocorticoids in Bone Remodeling

Glucocorticoids-2

Glucocorticoids

Glucocorticoids

Adrenal Steroids Mineralocorticoids &amp; Glucocorticoids

STRESS, GLUCOCORTICOIDS, AND YOUR BRAIN

Clinical Doses Glucocorticoids

GLUCOCORTICOIDS AND MINERALOCORTICOIDS

Antenatal Glucocorticoids and BPD

Lightman, S. L. &amp; George, C. L. (2013) Glucocorticoids—timing, binding and environment

Regulation of Stress Induced Cytokine Response by Glucocorticoids

Clinical use of glucocorticoids

Glucocorticoids And Their Effects On The Innate Immune System Of The CNS

Stress-dependent Glucocorticoids and Proinflammatory Cytokines Impair Wound Healing

Corticosteroids / Glucocorticoids

Glucocorticoids maintain human osteoclasts in the active mode of their resorption cycle

Adrenal Steroids Mineralocorticoids &amp; Glucocorticoids

Adrenal Steroids Mineralocorticoids & Glucocorticoids

Lightman, S. L. & George, C. L. (2013) Glucocorticoids—timing, binding and environment

Adrenal Steroids Mineralocorticoids & Glucocorticoids