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Research Safety

Research Safety. Ensuring compliance with state and federal regulations, preventing injuries while facilitating research. Hazards include. Biological Chemical Radiological/Lasers Fire/Life Safety Ergonomics Reproductive Health Emergency preparedness. EH&S is here to help.

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Research Safety

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  1. Research Safety Ensuring compliance with state and federal regulations, preventing injuries while facilitating research

  2. Hazards include • Biological • Chemical • Radiological/Lasers • Fire/Life Safety • Ergonomics • Reproductive Health • Emergency preparedness

  3. EH&S is here to help • Review and sign off on “Certificates of Compliance” from funding agencies • Assist researchers in lab renovations, remodels, high hazard equipment purchase/use • Evaluate hazards related to biological, radiological, chemical agents used in research • Report non-compliance or concerns to Deans, Chairs, and AVC Research

  4. Biological Safety and Controlled Substances

  5. Institutional Biosafety Committee (IBC) • Federally mandated for institutions that received NIH funding • Intended to assist researchers to determine risk • Faculty run, EH&S administered • Electronic submission system, IMEDRIS • Non-compliance could result in loss of funding to entire campus

  6. Institutional Biosafety Committee (IBC) Research protocols must be submitted for work involving: • Infectious Agents (herpes virus, Chlamydia, HIV, salmonella) • Recombinant DNA ( transgenic animals, human gene therapy, tg plants, viral vectors) • CDC Select Agents and Toxins (anthrax, botox, ricin) • Human/NHP material (stem cells, established cell lines, blood, etc)

  7. Controlled Substances and Chemical Precursors • Regulated by DEA • Schedule I-IV • Ketamine • Pentobarbital, Euthasol • Poppy sap • Cocaine • Chemicals used to create narcotics, street drugs • Piperidine • Thionyl Chloride

  8. Controlled Substances • Campus has 1 DEA license! • All deviations from DEA regs and UC policy jeopordize research for entire campus • Requirements include: • Submission of CSUA • Training • Personnel screening ( possible future background checks) • Inventory control, security, annual and unannounced inspections by CS staff

  9. Fire Safety

  10. Researchers use different type of hazardous materials Regulated by different state agencies Campus Fire Marshal regulates many of these materials by use of: State Fire code, CCR Title 19, NFPA building code regulations. . Fire/Life Safety

  11. Fire/Life Safety Regulated Chemical Materials examples include: • Explosives Regulated on a case by case basis • Pyrophorics Regulated by maximum allowable quantities per control area Permitted in sprinklered buildings only • Highly Toxics Regulated by maximum allowable quantities per control area • Flammable and Combustible Liquids, Gases, & Solids Regulated by maximum allowable quantities per control area

  12. Campus Fire Marshals Scott Jackson 824-9665 jacksons@uci.edu Lab Design & Construction Dale Saunders 824-4077 dsaunder@uci.edu Fire Prevention

  13. Responding to Cal/EPA Reporting Requirements for Nanomaterials

  14. What are Nanomaterials? . • Very Small particles, usually < 100nm in their longest dimension. • Poorly soluble. • The diameter of a human hair is ≈ 500,000 nm

  15. Nanoparticles Nanoflowers Single Wall Carbon Nanotube Rods, Wires, Shapes Quantum Nanodots

  16. Carbon nanotubes Bucky Balls Fullerenes Quantum Dots Core shells Dendrimers Diamondoids Nanoonions Nanofibers Nanowires Nanocomposites Nanorods Nanofilms Nanocapsules Nanoclusters Nanocrystals Examples of nanomaterials UC Irvine EH&S

  17. Variety of applications Improved target drug delivery systems for cancer treatment Sunscreens More efficient storage in batteries, fuel cells, efficient catalytic converters Protective and glare reducing coatings and paints Stain resistant clothing Food storage

  18. Nanomaterials in Consumer Products: The Personal Care Industry Leading the Way (Photo by David Hawxhurst-Woodrow Wilson International Center for Scholars.)

  19. What does government want? Letter to President Yudof and Chancellor • UC needs to provide answers to specific questions about nanomaterials we make or use on campus • Currently, not much information known about environmental impact and health and safety effects of nanomaterials UC Irvine EH&S

  20. UC GOAL Provide information about use of nanomaterials, disposal, and safe work practices, analytical procedures, fate and transport of these nanomaterials, amounts used and disposed

  21. Future Application of Data • Responses will help implement green initiative laws and “Toxics Information Clearinghouse” • Information will establish foundation for regulatory policy in California, nationally, internationally UC Irvine EH&S

  22. QUESTIONS?www.ehs.uci.edu Chemicals, Nanomaterials Rebecca Lally, 45730 rrlally@uci.edu Biologicals, Controlled Substances, Occupational Health Sheila Hedayati, 49888 shedayat@uci.edu Fire/Life Safety, Building Codes Scott Jackson, 49665 jacksons@uci.edu UC Irvine EH&S

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