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IMAGE 8. Membranoproliferative glomerulonephropathy. Diffuse glomerular thickening Hypercellularity of glomerulus ( cf membranous GN, which is NOT hypercellular ). IMAGE 9. IgA nephropathy (Berger disease = primary disease). Many appearances: Normal

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  1. IMAGE 8 Membranoproliferativeglomerulonephropathy • Diffuse glomerular thickening • Hypercellularity of glomerulus (cf membranous GN, which is NOT hypercellular)

  2. IMAGE 9 IgA nephropathy (Berger disease = primary disease) • Many appearances: • Normal • Mesangial widening and endocapillary proliferation (mesangioproliferativeglomerulonephritis) • Segmental proliferation confined to some glomeruli (focal proliferative glomerulonephritis) • Overt crescenticglomerulonephriti • Sample showsmesangeal expansion

  3. IMAGE 10 IgA nephropathy • Immunoperoxidase stain of IgA

  4. IMAGE 11 • Thinning of BM Thin membrane disease

  5. IMAGE 12 • Hyaline arteriosclerosis at arrows • Nodules at arrowheads (diffuse spread) Diffuse diabetic glomerulosclerosis

  6. IMAGE 13 Nodular diabetic glomerulosclerosis • Hyaline arteriosclerosis at arrowhead • Nodules at arrows

  7. IMAGE 14 Diabetic GBM thickening

  8. IMAGE 15 Fibrin caps in diabetic nephropathy

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