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ALSPAC Data

ALSPAC Data. Measures of Childhood Incontinence. Or, if you’re squeamish…. How many kittens do you own?. Repeated questions:. Repeated questions: - Binary. Zero. One. Repeated questions: - Ordinal. Zero. One. Two ~ DSM4 criterion. Repeated questions. Asked at: 4½ years ~ KK

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ALSPAC Data

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  1. ALSPAC Data Measures of Childhood Incontinence

  2. Or, if you’re squeamish…

  3. How many kittens do you own?

  4. Repeated questions:

  5. Repeated questions: - Binary Zero One

  6. Repeated questions: - Ordinal Zero One Two ~ DSM4 criterion

  7. Repeated questions • Asked at: • 4½ years ~ KK • 5½ years ~ KM • 6½ years ~ KP • 7½ years ~ KR • 9½ years ~ KU

  8. Why mixture models? • Previous work (clinical/epidemiological) has provided evidence for subgroups • Different aetilogies • Different comorbid factors • Different long-term outcomes • Variability in development poorly captured by standard growth models • Relapsing group

  9. BW frequencies (complete case)

  10. Infrequent bedwetting

  11. Frequent Bedwetting

  12. Planned models • LLCA replication of Croudace AJE model • Incorporate covariates into above • LLCA/LCGA models of frequent wetters (binary) • Assessment of gender invariance with knownclass • Parallel modelling of day/night wetting • Ordinal modelling of 3-level measures • Incorporate covariates • Risk of later binary outcome

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