NE 104.3

1. NE 104.3 Micronutrients: Trace Minerals and Toxic Metals

2. Trace Minerals • Chromium • Selenium • Iodine • Manganese, Molybdenum, Vanadium, Boron, Silicon

3. Chromium • The Blood Sugar Mineral! • Critical for Glucose/Insulin Regulation • Increases Insulin Sensitivity • Part of Glucose Tolerance Factor (GTF) • Made in the liver • Made up of: • Chromium • Niacin (B3) • 3 amino acids: glutamic acid, glycine, cysteine • Lowers cholesterol • Decreases cravings

4. Nutritional yeast or Brewers yeast (2Tbl/day) Meats esp organ meats Whole grains Wheat bran, Wheat germ Sea Veggies Potatoes SAD High Carb diet Refined Foods (90% removed in Refining) Depleted soil (US has greatest incidence of Cr deficiency due to low soil levels & increased processed foods) Chromium Sources/Chromium Depleters

5. Chromium: Indications For Supplementation • Blood Sugar Dysregulation • Metabolic Syndrome/Diabetes/Hypoglycemia • Weight Loss • Appetite Control • Lipid Management (High cholesterol, High TGL) • Acne (high chromium yeast works best)

6. Chromium Supplementation • No RDA • 200 mcg/day is suggested • 400-600 mcg is therapeutic (200 mcg with meals) • Chromium picolinate or polynicotinate • High chromium yeast, Chromiun enriched yeast • Glucose Tolerance Factor • Sea veggies

7. Selenium (Se) • The Anti Cancer Mineral! • Prevents damage to DNA • Prevents damage to cell membranes • Important anti-oxidant (part of ACES) • Works with Vitamin E • Component of glutathione peroxidase • Important enzyme system in the liver • Immune stimulant • Needed for thyroid hormone synthesis • Heavy metals cause Se depletion

8. Selenium • Deficient in >75% of Americans • Commercial fertilizers deplete it • Organic Foods have 4X the amount of Selenium as Commercial • One brazil nut has all the selenium you need for one day! (Murray & Pizzorno), Total Wellness)

9. Cancer Heart disease Inflammation Low immune function Low thyroid function Alcoholism Infertility Premature aging Macular degeneration High blood pressure Atherosclerosis Arthritis Diabetic neuropathy Low Levels of Selenium

10. Where do We Get Selenium? • Whole grains • Fish • Meat • Eggs • Brazil nuts • Wheat germ • Anti-dandruff shampoos

11. Selenium • No RDA • 200 mcg is suggested (is in a multi) • Take with other minerals & vitamins • Above 2000 mcg is toxic • Best forms: • Selenomethionine • High selenium yeast

12. Iodine • Used to make thyroid hormones • Thyroid adds iodine to tyrosine to make T4 & T3 • Modulates effect of estrogen on breast tissue (Murray) • Iodide = iodine complexed to sodium or potassium • RDA: 150mcg but controversial (Brownstein uses over 10 mg., Murray says 500 mcg max) • Dr David Brownstein: • Book: “Iodine, Why You Need It Why You Can’t Live Without It” • Gaby/Kharrasian/LEF caution Brownstein’s studies inconclusive. • Iodide supplementation may adversely affect thyroid function: hyperthyroid, autoimmune

13. Iodine Deficiency • Congenital and Adult Hypothyroidism • Growth retardation • Infertility • Miscarriage • Infant mortality • Fibrocystic Breasts • Breast Cancer

14. Reasons for Iodine Deficiency • Soil erosion • Low salt diets • Inadequate Intake • Chemicals with toxic halogens: • Bromine, fluorine, chlorine • Compete/Displace Iodine • Ubiquity of soy in processed food (goitrogenic)?

15. How Can We Get Enough Iodine? • Iodized salt • Sea food • Sea Veggies • Meat, Eggs, Dairy • Ocean plant supplements: kelp, dulse • Avoid goitrogens: bromide (bakery products), excess, unfermented soy, cruciferous veggies

16. Iodine Supplementation • Multivitamin mineral • Sea vegetable extracts: kelp • Iodoral • 5 mg Iodine, 7.5 mg Iodide per tablet • Use with caution! • Iodine supplementation may decrease selenium levels*

17. Safety concerns • Individuals with increased sensitivity to excess iodine intake • Excess iodine and thyroid cancer • Interaction with thyroid medication and others – must be closely monitored!

18. Toxic Metals

19. Toxic Metals • Sources • Industrial pollutants • Air, water, food • >100,000 man made chemicals exist in our environment • >1000 new chemicals added to our “diet” each year • CDC Study: 2400 adults/children: • Documented > 200 chemical toxins in blood, urine • CA Study: 60% of rivers have high levels of prozac, antibiotics and ritalin “ The One Hundred Year Lie,” R. Fitzgerald

20. Toxic Metals • Displace minerals • Affect • Neurological system • Liver, kidney, GI tract • Bones, teethe, joints • Immune function • Mitochondrial function • Fat soluble

21. Toxic Metals • Mercury • Amalgams, fungicides, pesticides, cosmetics, tattoos, laxatives, calomel lotion, paper products, fish, vaccines • Lead • Pipes, paint, ceramics, glass, soil, roadways, cosmetics, hair dyes, dolomite, newsprint • Cadmium • Cigarette smoke, coal burning, plastics, batteries, phosphate fertilizers, paints, soft drinks, refined foods, metal smelting

22. Toxic Metals • Aluminum • Cookware, cans, foil, antacids, baking powder, antiperspirants, margarine, buffered aspirin, bleached white flour • Arsenic • Pesticides, herbicides, pressure treated wood, photoelectric processes, seafood

23. Mercury • 3 Types • Inorganic mercury (amalgams) • Ethylmercury (vaccines) • Methylmercury ( seafood) • Most toxic • Easiest to absorb • Most persistent

24. Neurological impairment Anemia Depression Hypertension Interferes with EFAs/brain development Binds to enzymes, proteins, glutathione Inactivates enzymes Suppresses immunity Interferes with Se Increased risk CVD Associated with Candida overgrowth Mercury

25. Inactivates Zn, Fe enzyme systems Binds to Hemoglobin Displaces Ca in bone Deposits in aorta Suppresses immunity Deposits in kidneys, brain, adrenals, thyroid, liver Lead

26. Cadmium • Kidney toxicity • Hypertension • Inhibits liver detox • Competes with Zn • Suppresses immunity • Contributes to BPH • Contributes to bone fractures

27. Managing Toxic Metal Poisoning • Identify & Remove the source • E4H, Emphasize mineral rich foods • Chelation (“binding minerals,” good & bad) • EDTA - ethylenediamine tetraacetic acid • DMSA - Dimercaptosuccinic acid • DMPS – Dimercapto-1-propanesulfonic acid Chemical chelators

28. Selenium Vitamin E Zinc Apple pectin MSM Taurine “Chelorex” www.scienceformulas.com Chlorella Alginate (sea veggies) Cilantro Vitamin C Alpha Lipoic Acid N-Acetyl Cysteine L-Glutamine Herbs & Botanicals(Natural Chelators)