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Who is this Guy?. B.A. Chemistry ‘79 Baylor University M.D. and Residency ‘87 UTMB - Galveston Mohs Fellowship ‘88 Duke University Professor of Dermatology University of Arkansas Private Practice Little Rock, Arkansas. Scott Dinehart, MD. Conflict of Interest.
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Who is this Guy? B.A. Chemistry ‘79Baylor University M.D. and Residency ‘87UTMB - Galveston Mohs Fellowship ‘88Duke University Professor of DermatologyUniversity of Arkansas Private Practice Little Rock, Arkansas Scott Dinehart, MD
Conflict of Interest Speaker and Consultant for Genentech
Clinical and Practice Management Tips Scott M. Dinehart, MD
“Realize that acne can be made worse by refined carbohydrates and certain dairy products, particularly skim milk”
“Facial acne severity improved more on the low glycemic index diet” Reynolds, et al. Nutrients.Oct 2010;2(10):1060-72.
“Glycemic load and frequency of milk and ice cream ingestion were positively associated with acne” Ismail, et al. BMC Dermatol. 2012;12:13.
“Subjects adhering to a LGL diet resulted in clinical and histopathological improvements of acne” Kwon, et al. Acta Derm Vener. 2012;92(3):241-6.
“Regular consumption of sweets, nuts, chocolate, and oily foods were recognized as risk factors for acne while spicy foods and fasting were not associated with acne severity” Ghodsi, et al. J Invest Dermatol. Sep 2009;129(9):2136-41.
Causes • Lactoferrin, an anti-inflammatory milk protein • Hormones in milk • Insulin?
“Substitute high glycemic index foods for low glycemic index foods, and avoid refined carbohydrates whenever possible” Scott Dinehart, MD
Clinical History • A 44 year old physician has a changing mole on his back • You decide to biopsy the lesion using a shave technique
You Make the Call A. The lesion needs no re-excision B. The lesion can be re-excised but only needs a wider shave because the deep margin is clear C. The lesion needs full thickness excision D. A and B are correct approaches
You Make the Call A. The lesion needs no re-excision B. The lesion can be re-excised but only needs a wider shave because the deep margin is clear C. The lesion needs full thickness excision D. A and B are correct approaches
Re-excision of Dysplastic Nevi • Pathologist deserves a vote • Clinician deserves a vote • But in general….
“there is mounting evidence that re-excision of lesions with low-grade atypia (mild and moderate DN) may not be necessary, even when positive margins are found; the recurrence rates of these nevi are low, and there are no reports of subsequent development of melanoma in these lesions” Duffy et al. Arch Dermatol 148:259, 2012
May not need to re-excise mild to moderate dysplatic nevi • If you re-excise it is important to know if deep or lateral margins involved • If lateral margins present, can re-shave • Severely dysplastic nevi need full thickness re-excision with minimal margin
Dysplastic Nevi • Tip #1: Trend is not to re-excise mild and moderate dysplastic nevi • Tip #2: Work with your dermatopathologist. A shave removal can often work for mild or moderate dysplastic nevi that you want removed if only the lateral margin is involved • Tip #3: Start the shave removal more lateral to avoid lateral margin positives!
Use of a hair dryer • Hair dryers on “warm” can dry the scalp
Use of a hair dryer • Hair dryers on “cold” can be used to EXAMINE the scalp
Use of a hair dryer • Only needed on selected patients to find lesions on the scalp
“There are only two times when you need to consider doing a KOH examination”
KOH Preparation • Use KOH with DMSO (no need to heat) • Dip blade in KOH prior to scraping lesion (scale will stick to the blade) • Look on high power for hyphae (look like thin black lines)
Identify the “red dot” basal cell carcinoma