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Xi Zhang Shanghai Municipal Center for Disease Control

INTRODUCTION ( 介 绍 ). Xi Zhang Shanghai Municipal Center for Disease Control. Guideline( 目录 ). Brief Introduction of SCDC （ SCDC 简介） Introduction of Lab of Microbiology （微生物实验室 简介） Brief Introduction of Myself （个人介绍）. Sight Seeing of SCDC (SCDC 业务大楼 ).

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Xi Zhang Shanghai Municipal Center for Disease Control

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  1. INTRODUCTION(介 绍) Xi Zhang Shanghai Municipal Center for Disease Control

  2. Guideline(目录) • Brief Introduction of SCDC（SCDC简介） • Introduction of Lab of Microbiology （微生物实验室 简介） • Brief Introduction of Myself （个人介绍）

  3. Sight Seeing of SCDC(SCDC业务大楼)

  4. New Lab Buiding(SCDC实验大楼)

  5. Goals of SCDC(目 标) Established Public System • meet health needs • improve quality of citizen life • ensure the persistent social and economic development of the city.

  6. Goals and Objectives of SCDC(目 标) • To expand responsibility on public health to meet social and individual needs • To improve the ability of rapid response to the urgent events and disasters; • To offer high quality health services for community; • To improve the preventive medicine research level • To promote national and international collaboration

  7. MISSION of SCDC (任 务) • Policy making and planning • Surveillance and information synthesis • Implementation of prevention and intervention • Public health research • Prevention and health care service

  8. Shanghai Municipal Center for Disease Control and Prevention Shanghai Institute of Preventive Medicine Administration office Research and Education office Test Manage office Personnel & Security office Assents Manage office Association Manage office Quality control office Logistics office Financing (Auditing) office Capital Construction office Editorial Department Training Department Division for Health Information Division forcommunicableDiseaseControl&Prevention Division for Chronic Diseases Prevention Division for Environmental & Occupational Health Division for Health & Safety Assessment Division for Health Care Service Dept of Epidemic Prevention Dept of Chronic Diseases Prevention Dept of Occupational Health Office of Preventive Health Examination Dept of Food Health and Safety Dept of Immunization Vaccine Management Dept of Health Care for Children&Adolescents Dept of Environmental Health Research Dept of Environmental Health Evaluation Office of Medical Examination for Drivers Dept of Vector Control & Prevention Lab of Molecular Biology & Gene Dept of Nutrition Lab of ChemicalAnalysis Lab of Microbiology Dept of Occupational Health Examination Dept of Toxicology Dept of Tuberculosis Control&Prevention Dept of Parasitosis Control&Prevention Lab of Experimental Animal Dept of HIV/AIDS,STD Control & Prevention Dept of Disinfection Dept of Health Statistics Central library Dept of computer administration SCDC Organization Chart

  9. SCDC RESOURCE • Employee: More than 700 persons • Technical Employee: more than 530 persons • Lab area: 32,000m2 • Instrument capital: over 200 million Yuan (RMB)

  10. LAB MAMAGEMENT ORGANIZITION CHART 上海市疾病预防控制中心 上海市预防医学研究院 上海疾控安全健康保健评价中心 生物安全领导小组 中心（院）办公室 后勤管理科 质量管理科 （生物安全领导小组办公室） 检验管理科 科技教育科 人事保卫科 微 生 物 实 验 室 免疫规划实验室 结核病防治实验室 寄生虫病防治实验室 病媒生物防治实验室 消 毒 实 验 室 艾滋病性病麻风病 防治实验室 菌毒种与生物样品 保藏中心 职业卫生与 中毒控制实验室 公共卫生分子生物学 研究室 毒 理 室 理化分析实验室 环境卫生实验室 食品卫生与食源性 疾病防治实验室 营养卫生实验室 实验室供应中心 健康相关产品卫生评价实验室 环境职业场所卫生评价实验室 放射卫生实验室

  11. SCDC Lab Management • Accredited with ISO /IEC17025:1999 certification • Accredited with Metrology Certification • Pay more attention to lab safety and bio-safety • Employee technical training annual • Developing LIMS

  12. Tasks of Lab of Microbiology(微生物实验室的工作职责和任务） • To monitor pathogens contaminating in environment (water, air) , foods, air conditioners • To monitor infectious diseases • To do some research works for public health (especially in detection methods, food safety, professional health, environment health) • To take part in dealing with public health emergency affairs • To provide analysis data for surveillance and product safety. • To participate in and issue quality control plan • To provide professional and technical training for different microbiology lab

  13. Structure of Lab of Microbiology(微生物实验室组成） • Bacteria monitoring and testing section Respiratory bacteria group Enterobacterium group Vector borne bacteria group Serum antibody surveillance group • Virus monitoring and testing section Respiratory virus group Enterovirus group Hepatitis virus group Vector borne virus group Serum antibody surveillance group

  14. Structure of Lab of Microbiology(微生物实验室组成） Lab of Microbiology Bacteria section Viruses section Respiratory bacteria group Respiratory virus group Enterobacterium group Enterovirus group Surem antibody surveillance group Hepatitis virus group Vector borne Bacteria group Arbonia virus group

  15. Technical Platform of Lab of Microbiology • Pathogens isolation and identification • Immunoassay (ELISA, IFA, etal) • Molecular biology assay (PCR, PFGE, Ribo-printer, DNA Sequence tests)

  16. Pictures of Microbiology Lab Lab corridor A variety of microscope

  17. More Pictures Nucleic acid extraction machine Real-time PCR instrument

  18. More Pictures ATB for Bacteria identification Temple for Bacteria counting

  19. Bio-safety level-3 Laboratory

  20. Main co-operate Items • Join in the Global Salmonella Surveillance (GSS) • Join in the Pulse-Net Chine (which is co-operate with Pulse-Net USA) • Join in the WHO Influenza surveillance and monitoring Net • Join in the foods safety and inspects surveillance in China

  21. Bacteria Monitoring & TestingSection • Monitoring salmonella, shigella, Vibro Cholera, E.Coli O157:H7, Vibro Parahemolyticus, staphylococcus aureus, campylobacter，Listeria Monocytogenes et al in foods (pork, beef, seafood, milk, vegetables et al), water supply and diarrhea patients • Monitoring Legionalle bacillus in air conditioners, water distribution systems and patients • Monitoring Neisseria meningitis, Group A Streptococcus and other respiratory bacteria in patient and public areasy • Monitoring vector-borne pathegons • Monitoring and testing pathogens in foodborne diseases and waterborne diseases • Monitoring antibiotic sensitivity and antibiotic resistence • Monitoring antibody level in population

  22. Viruses Monitoring and Testing Section • Monitoring HAV ,HEV and Noro virus in seafood , water supply, riverhead and patients • Monitoring influenza and other respiratory viruses in publics and patients • Monitoring Avian influenza in publics and birds, poultries • Monitoring Japanese Encephalitis virus, Dengue fever virus and Hanta virus, et al in mosquito, mouse and patients • Monitoring Hepatitis virus such as HBV, HCV, HEV in patients • Monitoring other diarrhea viruses in patients • Monitoring hand-foot-mouth disease in children • Monitoring virus-Antibody levels in population

  23. Monitoring Results • Comma bacillus positive in HuangPu River and sea foods • Salmonella ,pathogenic E. coli positive in pork and beef • Parahaemorrhagic vibro positive in sea foods • Legionella bacillus positive in water distribution systems and central air conditioner chilled water supplys • HAV, Noro virus positive in sea foods • Dengue virus, Japanese encephalitis virus negative in mosquito and Hanten virus antibody positive in mouse

  24. The situation of Communicable disease in Shanghai,2007

  25. The situation of Communicable disease (part) in Shanghai,2007

  26. Personal Experience • The Chief of Microbiology Lab • Responsible for lab management, lab bio-safety, including quality and technical management • Over 20 years lab practice • Familiar with pathogens isolation, identification and molecular technique( such PCR and Real-time PCR) • Graduated from the School of Public Health, Fudan University

  27. Personal Research Field • Microbiology pollution surveillance and monitor in foods, water supply and central air conditioner • Pathogenic organisms detecting and results analysis in communicable disease patients • Pathogenic organisms rapid testing methods research • Search for unknown pathogens which causes communicated disease

  28. Goals of Fogarty Training • To understand the lab management here in California (lab safety, quality control) • To learn the research strategies and methods • To learn the planning & preparing of bioterrorism • To learn the public health emergency response strategies • To realize California’s culture, historical and social environment • To improve my English

  29. Thanks for • Fogarty International Center of NIH • California Department of Public Health, EHIB &EHLB • Faculty members of Fogarty International Training Program • All members in EHIB and EHLB

  30. THANK YOU !

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