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Chapter 14 Hallucinogenic Drugs

Chapter 14 Hallucinogenic Drugs. Mescaline Peyote cactus. Psilocybin Psilocybe mushrooms psilocybin  psilocin. LSD . Pharmacology of Hallucinogenic Drugs . Pharmacology of Hallucinogenic Drugs . LSD Trip (psychological effects) Onset Plateau Peak Come-down.

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Chapter 14 Hallucinogenic Drugs

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  1. Chapter 14 Hallucinogenic Drugs

  2. MescalinePeyote cactus

  3. PsilocybinPsilocybe mushrooms psilocybin  psilocin

  4. LSD

  5. Pharmacology of Hallucinogenic Drugs

  6. Pharmacology of Hallucinogenic Drugs LSD Trip (psychological effects) • Onset • Plateau • Peak • Come-down

  7. Pharmacology of Hallucinogenic Drugs Physiological effects • Activate sympathetic nervous system • Dilated pupils • Heart rate increase • Blood pressure increase • Body temperature increase • Dizziness • Nausea and vomiting

  8. Pharmacology of Hallucinogenic Drugs Most hallucinogens are 5-HT receptor agonists If you use a 5-HT receptor antagonists together with a hallunicongen, illusions and hallucinations disappear

  9. Pharmacology of Hallucinogenic Drugs Acquisition of an LSD/saline discrimination and attenuation of the drug stimulus cue

  10. Pharmacology of Hallucinogenic Drugs Acquisition of an LSD/saline discrimination and attenuation of the drug stimulus cue

  11. http://www.antidrug.health.am/img/haluc.jpg Pharmacology of Hallucinogenic Drugs Problems with hallucinogenic drugs • “Bad Trip” • Flashbacks • Psychotic breakdown

  12. Dissociative Anesthetics PCP

  13. Dissociative Anesthetics Ketamine crystals

  14. PCPSelf-administration of PCP into the nucleus accumbens shell by rats

  15. KetamineKetamine administration produces a dose-dependent increase in psychotic-like symptoms

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