160 likes | 881 Views
Chapter 14 Hallucinogenic Drugs. Mescaline Peyote cactus. Psilocybin Psilocybe mushrooms psilocybin psilocin. LSD. Pharmacology of Hallucinogenic Drugs. Pharmacology of Hallucinogenic Drugs. LSD Trip (psychological effects) Onset Plateau Peak Come-down.
E N D
Pharmacology of Hallucinogenic Drugs LSD Trip (psychological effects) • Onset • Plateau • Peak • Come-down
Pharmacology of Hallucinogenic Drugs Physiological effects • Activate sympathetic nervous system • Dilated pupils • Heart rate increase • Blood pressure increase • Body temperature increase • Dizziness • Nausea and vomiting
Pharmacology of Hallucinogenic Drugs Most hallucinogens are 5-HT receptor agonists If you use a 5-HT receptor antagonists together with a hallunicongen, illusions and hallucinations disappear
Pharmacology of Hallucinogenic Drugs Acquisition of an LSD/saline discrimination and attenuation of the drug stimulus cue
Pharmacology of Hallucinogenic Drugs Acquisition of an LSD/saline discrimination and attenuation of the drug stimulus cue
http://www.antidrug.health.am/img/haluc.jpg Pharmacology of Hallucinogenic Drugs Problems with hallucinogenic drugs • “Bad Trip” • Flashbacks • Psychotic breakdown
Dissociative Anesthetics Ketamine crystals
PCPSelf-administration of PCP into the nucleus accumbens shell by rats
KetamineKetamine administration produces a dose-dependent increase in psychotic-like symptoms