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Asthma – 2005 “Why We Do the Things We Do” A Miniature Literature Review. Michael E. Ruff, MD Dallas, Texas. Photo: Personal collection, Dr. Dennis Williams Pharm.D. Effect of Inhaled Corticosteroids on Inflammation. E = Epithelium BM = Basement Membrane.
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Asthma – 2005“Why We Do the Things We Do”A Miniature Literature Review Michael E. Ruff, MD Dallas, Texas
Effect of Inhaled Corticosteroids on Inflammation E = Epithelium BM = Basement Membrane Pre– and post–3-month treatment with budesonide (BUD) 600 mcg b.i.d. Laitinen et al. J Allergy Clin Immunol. 1992;90:32-42. Reprinted with permission.
Mean Annual Increase in FEV1During ICS Therapy 12 10 8 6 4 2 0 Annual Change in % Predicted FEV1 <2 2-3 3-5 >5 Asthma Duration at Start of ICS therapy (yrs) Agertoft L, Pederson S. Respir Med. 1994; 88:373-381.