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Part III. Amy L. McIntosh, MD Pediatric Orthopedic Surgeon Mayo Clinic Rochester, Minnesota. Medical Therapy. Supplements Over-the-counter medicines Prescription medicines Injection therapy. Supplements. Little scientific evidence for/against products Not subject to FDA regulations
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Part III Amy L. McIntosh, MD Pediatric Orthopedic Surgeon Mayo Clinic Rochester, Minnesota
Medical Therapy • Supplements • Over-the-counter medicines • Prescription medicines • Injection therapy
Supplements • Little scientific evidence for/against products • Not subject to FDA regulations • Reasonable evidence for glucosamine / chondroitin helping with arthritic symptoms • No evidence for other compounds
OTC Medicines • Tylenol • NSAIDs – Ibuprofen (Advil) and Naprosyn (Aleve) • Equally effective in all major studies • Quite safe when taken with supervision • Stomach ulcers • Kidney trouble
Prescription Medicines • Prescription NSAIDs • Celebrex, Mobic, etc • No better than ibuprofen or naprosyn in comparable doses • Benefits for select patients • Primary benefit is convenience • Cardiovascular risks unknown
Prescription Medicines - Opiates • Synthetic derivatives of morphine • Effective • But… tolerance building and habit forming • Frequent depression and side effects • Used very selectively and carefully under specialty supervision
Physical Therapy • Important aspect of joint care in SS • Particularly important before and after any surgery
Injection Therapy • Injection of cortisone or hyaluronic acid derivatives • Effective in ~2/3rds patients • Effect often fades • Safe for up to 3-4 times/year
Surgical Treatment • Fusion • Arthroscopy • Realignment / reshaping • Joint replacement
Fusion • Traditional treatment for arthritis in the young • “No motion, no pain” • Not for patients with multiple joint involvement • Spine, ankle, wrist possible exceptions
Arthroscopy • Low morbidity outpatient procedure • Doesn’t “burn” bridges • Effective against well defined targets • Focally torn cartilage • Not effective for generalized joint pain or arthritis
Realignment Procedures - Knee • Surgically change alignment to “offload” worn area • Delay need for joint replacement
Realignment Procedures - Hip Impinging bump on the edge of a malformed femoral head (ball)