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Pick a trial set of genes common to both platforms (region A) to define the GSVD

Pick a trial set of genes common to both platforms (region A) to define the GSVD. Perform GSVD and identify genes in microarray dataset (region A) co-expressing, in the overlapping subspace spanned by arraylets with θ k ≈0, with genes from Q-PCR dataset (region A). Assess suitability of the

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Pick a trial set of genes common to both platforms (region A) to define the GSVD

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  1. Pick a trial set of genes common to both platforms (region A) to define the GSVD Perform GSVD and identify genes in microarray dataset (region A) co-expressing, in the overlapping subspace spanned by arraylets with θk≈0, with genes from Q-PCR dataset (region A) Assess suitability of the set of genes defining the GSVD: how many known gene-pairs are co-expressing in the subspace? # of co-expressing gene-pairs around background levels # of co-expressing gene-pairs significantly above background Use this GSVD to identify genes in microarray dataset (region B) co-expressing, in the overlapping subspace spanned by arraylets with θk≈0, with genes of interest from Q-PCR dataset (region C)

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