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Cpx two-component system. s E heat-shock response. Stress misfolded envelope proteins. RseB. CpxP. DegS. periplasm. signal transmission. CpxA. cytoplasm. RseA. s E. CpxR. ATP. ˜ P. regulon CpxR : degP/htrA, dsbA, ppiA, ppiD, cpxRA, cpxP, spy….
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Cpx two-component system sE heat-shock response Stress misfolded envelope proteins RseB CpxP DegS periplasm signal transmission CpxA cytoplasm RseA sE CpxR ATP ˜P regulon CpxR :degP/htrA, dsbA, ppiA, ppiD, cpxRA, cpxP, spy… regulon sE :degP/htrA, fkpA, dsbC, skp, surA, rpoE, rpoH,…