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Enzymes

Enzymes. pp 96 - 102. Enzymes. All enzymes are proteins; not all proteins are enzymes. Most enzymes have an – ase ending. ATPase amylase. Enzymes. enzyme - . Enzymes. Substrate – . Steps to Enzyme Reactions. Write out the 5 steps for an enzyme catalyzing a reaction.

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Enzymes

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  1. Enzymes pp 96 - 102

  2. Enzymes All enzymes are proteins; not all proteins are enzymes. Most enzymes have an –aseending. ATPase amylase

  3. Enzymes enzyme -

  4. Enzymes Substrate–

  5. Steps to Enzyme Reactions Write out the 5 steps for an enzyme catalyzing a reaction

  6. Substrate Binding active site

  7. Substrate Binding R-groups

  8. Enzymes activation energy  EA

  9. Reaction Progression Reaction Progession

  10. Enzyme Energy Enzymes lower the activation energy (EA) of reactions.

  11. enzyme-substrate complex Substrate Binding induced-fit model -

  12. Substrate Binding Enzymes reduce EA by:

  13. Enzyme Limitations

  14. Enzyme Limitations

  15. Limitations of Enzymes Why do enzymes operate at an optimal temperature and pH?

  16. Enzyme Limitations cofactors– coenzymes– An apoenzymeis

  17. Enzyme Inhibition competitive inhibitor – noncompetitive inhibitor –

  18. Enzyme Inhibition

  19. Enzyme Regulation allosteric site – allosteric activator – allosteric inhibitor –

  20. Allosteric Sites

  21. Feedback Inhibition A, B, C and D are molecules along a metabolic pathway. E1, E2 and E3 are enzymes required for this metabolic pathway. D is an allosteric inhibitor of E1.

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