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Energy Metabolism & Diseases of Modern Civilization: Part I: Basics

Energy Metabolism & Diseases of Modern Civilization: Part I: Basics. Johannes Klein, University of Lübeck, Germany. Energy Metabolism. Cardiovascular Complications. Colon Cancer. Overweight. Diabetes. Ageing. Tumours. Lipid Abnormalities. High Blood Pressure. Altered Life Span.

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Energy Metabolism & Diseases of Modern Civilization: Part I: Basics

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  1. Energy Metabolism & Diseases of Modern Civilization: Part I: Basics Johannes Klein, University of Lübeck, Germany

  2. Energy Metabolism Cardiovascular Complications Colon Cancer Overweight Diabetes Ageing Tumours Lipid Abnormalities High Blood Pressure Altered Life Span Breast Cancer

  3. Was ist Adipositas? Definitionen und Meßmethoden

  4. Adipositas-Meßmethoden: Körpergewicht/Broca-Index BMI (Quetelet‘s Index) Waist circumference Waist to hip ratio Bioimpedanz Computertomographie/DEXA

  5. Größe: 1,75 m, BMI: 25 = 77 kg Body Mass Index (BMI): KG (kg)/[Größe (m)]2 BMI < 25: Normalgewicht BMI > 25: Übergewicht BMI > 30: Adipositas I BMI > 35: Adipositas II BMI > 40: Adipositas III

  6. Größe: 1,75 m, BMI: 30 = 93 kg

  7. Größe: 1,75 m, BMI: 40 = 123 kg

  8. Waist to Hip Ratio (WHR) • 0,9 men, • 0,85 women

  9. Ist eine „statische“ Adipositas-Definition sinnvoll?

  10. Was ist Diabetes? Definitionen

  11. 100

  12. Diabetes: Diagnose-Kriterien An zwei verschiedenen Tagen je ein Kriterium: • Diabetessymptome i. Zshg. mit Plasmaglukose > 200 mg/dl • Plasmaglukose > 126 mg/dl nach Nahrungskarenz > 8 h • Plasmaglukosekonzentration > 200 mg/dl 2 h nach oraler Glukose- Belastung (75 g)

  13. Was ist das Metabolische Syndrom? Definitionen

  14. WHO criteria 1999

  15. Change to novel criteria 2001: Adult Treatment Panel III consensus

  16. Useful websites: http://www.obesityonline.org/slides/index.cfm http://www.idf.org/home/index.cfm http://www.nhlbi.nih.gov/guidelines/obesity/practgde.htm

  17. Sie sollten nach der heutigen Vorlesung Fragen zu folgenden Themen beantworten können: • Epidemiologie und medizinische Risiken von Übergewicht und Diabetes • Meßmethoden und Definition von Übergewicht • Definition von Diabetes • Definition des Metabolischen Syndroms

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