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Prediction of interactions. Gene fusion. Gene neighbours. human. X. X. X. X. X. X. X. drosophila. elegans. X. X. X. X. X. X. X. mouse. Gene co-ocurrence. 3. 2. 2. 2. 2. phylogenies. Proteína B. Proteína A. Profiles (phylogeny). Expand interactions :
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human X X X X X X X drosophila elegans X X X X X X X mouse Gene co-ocurrence 3 2 2 2 2
phylogenies Proteína B Proteína A
Expand interactions: Using “interologs” DIP COG members
U n i v e r s i t a t P o m p e u F a b r a Baldomero Oliva Miguel Surface and core regions CORE VOLUME
U n i v e r s i t a t P o m p e u F a b r a Baldomero Oliva Miguel
U n i v e r s i t a t P o m p e u F a b r a Baldomero Oliva Miguel
U n i v e r s i t a t P o m p e u F a b r a Baldomero Oliva Miguel Convolution function: Obtain the maximum C
U n i v e r s i t a t P o m p e u F a b r a Baldomero Oliva Miguel Convolution function by Fourier Transform
U n i v e r s i t a t P o m p e u F a b r a Baldomero Oliva Miguel
U n i v e r s i t a t P o m p e u F a b r a Baldomero Oliva Miguel
U n i v e r s i t a t P o m p e u F a b r a Baldomero Oliva Miguel
U n i v e r s i t a t P o m p e u F a b r a Baldomero Oliva Miguel
STRING use of database http://string.embl.de
GRAPH Depth 2
A-B 4.2.1.2 1.1.1.37 Oxalo-acetato Malato Fumarato
Pathway based in common substrates and products (except water)
Reference Reference Test Test sample sample sample sample RNA RNA extraction extraction mRNA Reverse Reverse Cy5 Cy5 - - dCTP Cy3 Cy3 - - dCTP transcription transcription cDNA cDNA - - Cy3 Cy3 cDNA cDNA - - Cy5 Cy5 - cDNA or oligo microarray Dr. L. Sumoy (CRG)
pH 7 4 tumor metastasis metastasis tumor Mw 68.8 7505 4511 8401 6405 8301 28.4 2303 5201 8204 2202 7202 8201 5203 21.7 7201 7109 7115 7004 16.8 5004 9.1 Dra. A. Sierra (IRO)
Galectin Tubulin 5 HSP27 STRING database DIP database Predicción estructural Cathepsin D Prdx 4 ATP synthase Laminin R Glyoxalase Proteinas identificadas Proteinas propuestas
FUNCIONAL GROUP (GO cluster) A FUNCIONAL GROUP (GO cluster) B