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Writing a Fundable NIH K-Series Application. My Background and why it was important to my path. I received my BS from UC Irvine, my MD from Medical College of Wisconsin, pediatric residency at CHLA and pediatric cardiology fellowship at CHLA.
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My Background and why it was important to my path. • I received my BS from UC Irvine, my MD from Medical College of Wisconsin, pediatric residency at CHLA and pediatric cardiology fellowship at CHLA. • I had always participated in research but I did not take the reins of a project until I was a cardiology fellow. • I enjoyed research when I was with a mentor who cared about my education, however, I never took ownership of a project. • I did not understand how to write for scientific audiences. Know your strengths and exploit them but also know your limitations and address them.
The two most important things to a successful junior career • Mentor – both primary and secondary • Your desire to pursue research
The specific aims page is where it all starts and will set the tone for your entire grant. Don’t rush or minimize the importance of it. • Write and re-write multiple times with your mentor. • Make sure you have a relationship with your mentor that allows for a lot of one on one interaction with this process • This is where you can judge your own mentor’s desire to help. • When you are done, ask another researcher to read it, preferably someone who has experience reviewing grants
Five Elements of a Summary Statement – it is important to understand your strengths and limitations • Candidate • Training Background • Publications • “sustained progress” • “dedicated” • Career Development Plan/Career Goals & Objectives/Plan to Provide Mentoring • Plan for progression – ok to give a timeline to get an R • Secondary degree/education
Five Elements of a Summary Statement – it is important to understand your strengths and limitations • Research Plan • All aims are related and achieve a specific goal/address primary hypothesis • Methodology • “what if your sub-hypotheses are wrong” – you have to think about how your plan addresses being wrong • Mentor(s), Co-Mentor(s), Consultant(s), Collaborator(s) • NIH funding current • NIH track record • Preferably at the same institution • Must have outside consultant(s)
Five Elements of a Summary Statement – it is important to understand your strengths and limitations • Environment and Institutional Commitment to the Candidate • Be clear about your lab/institution, what is available to you – cores, animal labs/husbandry. • Highlight your team! • Support staff – how will you get the work done, because they know it is not going to be you alone. And if you paint a picture of doing it all yourself, they will mark you down. The ideas and planning are yours but the details take a team. • The division chief and mentor letters need to be explicit about protected time and dedication to you as a scientist.
Questions Jon Detterich: jdetterich@chla.usc.edu