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mutations

mutations. Latin for mistake Most mutations are neutral Little or no effect. 1. Mutations are changes in genetic material. Major mutations are often harmful . Genetic disorders Types of cancer. Mutations. Harmful, Helpful or Neutral?. Some mutations are beneficial

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mutations

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  1. mutations

  2. Latin for mistake Most mutations are neutral Little or no effect 1. Mutations are changes in genetic material

  3. Major mutations are often harmful. Genetic disorders Types of cancer Mutations

  4. Harmful, Helpful or Neutral?

  5. Some mutations are beneficial Source of genetic variance. mutations

  6. 2. Types of Mutations • Gene mutations – occur in a single gene. • Point mutations – occur in one or a few nucleotides. • Substitution mutation – base substituted • usually affect no more than one amino acid. • THE FAT CAT ATE THE RAT

  7. 2. Types of Mutations • Gene mutations – occur in a single gene. • Point mutations – occur in one or a few nucleotides. • Substitution mutation – base substituted • usually affect no more than one amino acid. • THE FAT CAT ATE THE RAT THE FTT CAT ATE THE RAT

  8. 2. Types of Mutations ii. Frame shift mutations 1. Insertion mutations – extra nucleotide is inserted into the sequence THE FAT CAT ATE THE RAT

  9. 2. Types of Mutations ii. Frame shift mutations 1. Insertion mutations – extra nucleotide is inserted into the sequence THE FAT CAT ATE THE RAT THH EFA TCA TAT ETH ERA T

  10. 2. Types of Mutations • 2. Deletion mutations • THE FAT CAT ATE THE RAT

  11. 2. Deletion mutations THE FAT CAT ATE THE RAT TEF ATC ATA TET HER AT 2. Types of Mutations

  12. b. Chromosomal mutations i. changes the structure of the entire chromosome 2. Types of Mutations

  13. 2. Types of Mutations • 1. Deletions • 2. Duplications • 3. Inversions • 4. Translocations

  14. 2. Types of Mutations • 1. Deletions • THE FAT __ ATE THE RAT • 2. Duplications • 3. Inversions • 4. Translocations

  15. 2. Types of Mutations • 1. Deletions • THE FAT __ ATE THE RAT • 2. Duplications • THE FAT CAT CAT ATE THE RAT • 3. Inversions • 4. Translocations

  16. 2. Types of Mutations • 1. Deletions • THE FAT __ ATE THE RAT • 2. Duplications • THE FAT CAT CAT ATE THE RAT • 3. Inversions • THE CAT FAT ATE THE RAT • 4. Translocations

  17. 2. Types of Mutations • 1. Deletions • THE FAT __ ATE THE RAT • 2. Duplications • THE FAT CAT CAT ATE THE RAT • 3. Inversions • THE CAT FAT ATE THE RAT • 4. Translocations • THE ATE THE FAT CAT RAT

  18. Mutation Lab • TATATACCGCGATAGAAA • Write the correct nucleotide sequence according to the base pairing rule. • “decipher” the code for the: complimentary DNA strand, mRNA, tRNA and amino acids. • Label DNA, mRNA, tRNA, replication, transcription and translation • On the back, Retrace the code with the mutation given to each group.

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