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MUSCLE AND NERVE

MUSCLE AND NERVE. unique to animals conduct electricity (controlled fashion) allow for movement. Actin-Myosin model (board) EXPLAINS: MUSCLE SHORTENING MUSCLE FORCE GENERATION OR “CONTRACTION”. Molecular Basis of Muscle Function. Mechanics of Contraction. Muscle cell is unit

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MUSCLE AND NERVE

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  1. MUSCLE AND NERVE unique to animals conduct electricity (controlled fashion) allow for movement Human Anatomy, Larry M. Frolich, Ph.D.

  2. Actin-Myosin model (board) EXPLAINS: MUSCLE SHORTENING MUSCLE FORCE GENERATION OR “CONTRACTION” Molecular Basis of Muscle Function Human Anatomy, Larry M. Frolich, Ph.D.

  3. Mechanics of Contraction • Muscle cell is unit • Role of actin/myosin • Action potential or depolarization of membrane makes cell “contract” • (motor neuron action potential stimulates muscle membrane depolarization) Fig. 10.4 Human Anatomy, Larry M. Frolich, Ph.D.

  4. Visualizing muscle contraction How actin-myosin complex (sarcomere) shorten muscle Fig. 10.7 Human Anatomy, Larry M. Frolich, Ph.D.

  5. From Actin-Myosin to Whole Muscle M & M, Fig. 4.17 for muscle types Human Anatomy, Larry M. Frolich, Ph.D.

  6. Skeletal Muscle Tissue(each skeletal muscle is an organ) • Cells • Long and cylindrical, in bundles • Multinucleate • Obvious Striations • Skeletal Muscles-Voluntary • Connective Tissue Components: • Endomysium-between fibers • Perimysium-surrounds bundles • Epimysium-surround whole muscle • Attached to bones, fascia, skin • Origin & Insertion Human Anatomy, Larry M. Frolich, Ph.D.

  7. Smooth Muscle Tissue • Cells • Single cells, uninucleate • No striations • Smooth Muscle-Involuntary • 2 layers-opposite orientation (peristalsis) • Surrounds hollow organs, blood vessels • Connective Tissue Component • Endomysium: surrounds cells Human Anatomy, Larry M. Frolich, Ph.D.

  8. Cardiac Muscle • Cells • Branching, chains of cells • Single or Binucleated • Striations • Connected by Intercalated discs • Cardiac Muscle-Involuntary • Myocardium-heart muscle • Pumps blood through vessels • Connective Tissue Component • Endomysium: surrounding cells Human Anatomy, Larry M. Frolich, Ph.D.

  9. Neurons are biggest cells in body Two basic types motor sensory Messages travel by membrane depolarization Schwann cells are insulation in peripheral nerves (none in CNS) NERVOUS TISSUE [Thought game: trip from sensory input (e.g., hot stove) to motor response (e.g., pull back hand] Human Anatomy, Larry M. Frolich, Ph.D.

  10. Human Anatomy, Larry M. Frolich, Ph.D.

  11. Human Anatomy, Larry M. Frolich, Ph.D.

  12. NEURONAL JUNCTIONSNeuron-neuron or neuron-muscle • NEURO-MUSCULAR JUNCTION Where neuron transmits signal to muscle to generate action potential • SYNAPSE: cell junction where neurons communicate Human Anatomy, Larry M. Frolich, Ph.D.

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