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A. iNOS COX-2. iNOS COX-2. iNOS COX-2. iNOS COX-2. 16. 14. 14. iNOS. 12. iNOS. 12. 10. Fold increase over control. 8. 10. Cox-2. Cox-2. 6. Fold increase over control. 8. 4. 6. b- actin. b- actin. 2. 4. 0. 2.
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A iNOS COX-2 iNOS COX-2 iNOS COX-2 iNOS COX-2 16 14 14 iNOS 12 iNOS 12 10 Fold increase over control 8 10 Cox-2 Cox-2 6 Fold increase over control 8 4 6 b-actin b-actin 2 4 0 2 - + + + + + + + 10 20 10 20 SP (mM) SP (mM) - + + + + + + + 10 20 10 20 SP (mM) SP (mM) - + + + + + + + 10 20 10 20 SP (mM) SP (mM) - + + + + + + + 10 20 10 20 SP (mM) SP (mM) LPS (1 mg/ml) LPS (1 mg/ml) SNP (200 mM) SNP (200 mM) 0 BV (5 mg/ml) BV (5 mg/ml) BV (5 mg/ml) BV (5 mg/ml) Melittin (10mg/ml) Melittin (10mg/ml) Melittin (10mg/ml) Melittin (10mg/ml) B 14 16 14 12 12 10 iNOS Fold increase over control iNOS Fold increase over control 10 8 8 6 Cox-2 Cox-2 6 4 4 2 2 b-actin b-actin 0 0