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Ultrasound Guided Botulinum Toxin Injection for Sialorrhoea in Parkinson s Disease; Evidence, Technique and Outcomes

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Ultrasound Guided Botulinum Toxin Injection for Sialorrhoea in Parkinson s Disease; Evidence, Technique and Outcomes

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    1. Ultrasound Guided Botulinum Toxin Injection for Sialorrhoea in Parkinson’s Disease; Evidence, Technique and Outcomes Background Sialorrhoea: inability to control oral secretions, causing excess saliva in oropharynx. Parkinson’s Disease (PD) affects 120,000 people in the UK and up to 80% of patients suffer with sialorrhoea. Sialorrhoea may cause drooling, social embarrassment and severely affect quality of life. There are also concerns it may predispose to aspiration pneumonia. Established pharmacological treatments are often ineffective or poorly tolerated. USS-guided injection of botulinum toxin into the salivary glands is a highly effective treatment but is not widely offered in many centres. This treatment has been shown to decrease saliva production in up to 90% of patients and significantly improves quality of life. In our institution, a one-stop clinic is offered with a radiologist and physician working together. This provides a successful environment for symptom evaluation and the provision of USS-guided botulinum toxin injections. Evidence

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