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OCULAR PATHOLOGY CASE CONFERENCE

OCULAR PATHOLOGY CASE CONFERENCE. Chirag Patel, M.D. (PGY-2) Hilary Nikols, M.D. (PGY-3) Mark Becher, M.D. Louise Mawn, M.D. October 20, 2008. Case #3. Case #3 (cont’d). Case 3 : Basal Cell Carcinoma. Case 3 : Basal Cell Carcinoma. Case #5. Case #5 (cont’d). Case #5 (cont’d).

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OCULAR PATHOLOGY CASE CONFERENCE

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  1. OCULAR PATHOLOGY CASE CONFERENCE Chirag Patel, M.D. (PGY-2) Hilary Nikols, M.D. (PGY-3) Mark Becher, M.D. Louise Mawn, M.D. October 20, 2008

  2. Case #3

  3. Case #3 (cont’d)

  4. Case 3: Basal Cell Carcinoma

  5. Case 3: Basal Cell Carcinoma

  6. Case #5

  7. Case #5 (cont’d)

  8. Case #5 (cont’d)

  9. Case 5: capillary hemangioma

  10. Case 5: capillary hemangioma

  11. Case #6

  12. Case #6 (cont’d)

  13. Case #6 (cont’d)

  14. Case 6: vascular malformation, possibly arteriovenous masson

  15. Case 6: vascular malformation, possibly arteriovenous masson

  16. Case 6: vascular malformation, possibly arteriovenous masson

  17. Case #7

  18. Case #7 (cont’d)

  19. Case #7 (cont’d)

  20. Case 7: dermoid

  21. Case #8

  22. Case 8: Retinoblastoma

  23. Case 8: Retinoblastoma

  24. Case 8: Retinoblastoma

  25. Case 8: Retinoblastoma PAS

  26. Case 8: Retinoblastoma • Deletion of both RB1 tumor suppressor genes • Hereditary form 40% • Germ cell line mutation; loss of one gene at embryogenesis • Usually presents bilaterally and early • Risk of second malignancy • Non-hereditary form 60% • Somatic mutation at level of retinal cell • Usually unilateral and presents later in childhood

  27. Case #9

  28. Case #9 (cont’d)

  29. Case #9 (cont’d)

  30. Case #9 (cont’d)

  31. Case 9: Embryonal rhabdomyosarcoma

  32. Case 9: Embryonal rhabdomyosarcoma

  33. Case 9: embryonal rhabdomyosarcoma desmin myoD1 myogenin

  34. Case #10

  35. Case #10 (cont’d)

  36. Case #10 (cont’d)

  37. Case 10: cavernous hemangioma

  38. Case 10: cavernous hemangioma

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