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H ow the Ocean Heals Lyme Disease. Kristen T. Honey, PhD khoney@stanford.edu. Integrative Lyme Solutions Academy of Comprehensive Integrative Medicine June 22, 2013, Dallas, TX. Talk Outline. Share and encourage dialogue for pragmatic solutions :. My healing journey :
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How the OceanHeals Lyme Disease Kristen T. Honey, PhD khoney@stanford.edu Integrative Lyme Solutions Academy of Comprehensive Integrative Medicine June 22, 2013, Dallas, TX
Talk Outline • Share and encourage dialogue for pragmatic solutions: • My healing journey: • 100% Lyme recovery possible with • holistic approach, tenacity, resilience.
Talk Outline • Share and encourage dialogue for pragmatic solutions: • My healing journey: • 100% Lyme recovery possible with • holistic approach, tenacity, resilience. • Oligotherapy: • Healing power of trace minerals for therapeutic support, especially bioavailable minerals from ocean.
Talk Outline • Share and encourage dialogue for pragmatic solutions: • My healing journey: • 100% Lyme recovery possible with • holistic approach, tenacity, resilience. • Oligotherapy: • Healing power of trace minerals for therapeutic support, especially bioavailable minerals from ocean. • Nano-mineral treatments: • Emerging science & technology for new frontiers of treatments with nano-silver and nano-gold to eradicate Lyme-related infections and symptoms.
Talk Outline • Share and encourage dialogue for pragmatic solutions: • My healing journey: • 100% Lyme recovery possible with • holistic approach, tenacity, resilience. • Oligotherapy: • Healing power of trace minerals for therapeutic support, especially bioavailable minerals from ocean. • Nano-mineral treatments: • Emerging science & technology for new frontiers of treatments with nano-silver and nano-gold to eradicate Lyme-related infections and symptoms. • Curing Lyme: • YES we can! (with patient self-care & partnership)
Talk Outline • Share and encourage dialogue for pragmatic solutions: • My healing journey: • 100% Lyme recovery possible with • holistic approach, tenacity, resilience. • Oligotherapy: • Healing power of trace minerals for therapeutic support, especially bioavailable minerals from ocean. • Nano-mineral treatments: • Emerging science & technology for new frontiers of treatments with nano-silver and nano-gold to eradicate Lyme-related infections and symptoms. • The Lyme Cure: • YES we can! (with patient self-care & partnership) Problem solving for recovery through a lens of ecology & integrative systems thinking => fresh perspective on Lyme disease
Together for Lyme SolutionsPart 1: My Story • Share and encourage dialogue for pragmatic solutions: Problem solving for recovery through a lens of ecology & integrative systems thinking => fresh perspective on Lyme disease
My Healing Journey From Stanford PhD… to food stamps… and back! • 1999 tick bites • Decade of mystery symptoms & increasing illness • 2009 collapse with late-stage, neurological Lyme disease
My Healing Journey From Stanford PhD… to food stamps… and back! • Healing is a full-time job • Lifestyle overhaul, which not all patients will do (diet, EMFs, etc.) • Integrated approach with emotional grief of loss & surrender
My Healing Journey From Stanford PhD… to food stamps… and back! • Healing is a full-time job • Lifestyle overhaul, which not all patients will do (diet, EMFs, etc.) • Integrated approach with emotional grief of loss & surrender Note: Lyme patients can be very skilled at hiding symptoms by showing themselves only on “good” days... …until there are not enough hours in a day to “fake it” Volatile symptoms Volatile disease
My Healing Journey What can one patient, or one practitioner, do? Be the change! YOU are the leader you’ve been waiting for! Steve Schneider
My Healing Journey 10 years, six months & many doctors later… Patient #1 goal: Navigate way to a medical champion, LLMD, & integrative team for healing support on ALL levels 5th Spirit (5 SB) 4th Intuitive (4 IB) 3rd Mental (3 MB) 2nd Energy Body (2 EB) 1st Physical Body (1 PB) Dr. Klinghardt’s 5 levels of healing
My Healing Journey 10 years, six months & many doctors later… Patient #1 goal: Navigate way to a medical champion, LLMD, & integrative team for healing support on ALL levels 5th Spirit (5 SB) 4th Intuitive (4 IB) 3rd Mental (3 MB) Successful Recovery: Mind-body-spirit work for comprehensive, holistic healing 2nd Energy Body (2 EB) 1st Physical Body (1 PB) Dr. Klinghardt’s 5 levels of healing …although many paths to Rome for recovery
My Healing Journey Modified Dr. Klinghardt’s 5 levels of healing to reflect “biggest bang for the buck” 5th Spirit (5 SB) 4th Intuitive (4 IB) 3rd Mental (3 MB) Subjective Reality Objective Reality 2nd Energy Body (2 EB) 1st Physical Body (1 PB)
My Healing Journey Modified Dr. Klinghardt’s 5 levels of healing plus CONTEXT MATTERS, a la Bruce Lipton 5th Spirit (5 SB) 4th Intuitive (4 IB) 3rd Mental (3 MB) 2nd Energy Body (2 EB) 1st Physical Body (1 PB)
My Healing Journey Modified Dr. Klinghardt’s 5 levels of healing plus CONTEXT MATTERS, a la Bruce Lipton 5th Spirit (5 SB) 4th Intuitive (4 IB) 3rd Mental (3 MB) 2nd Energy Body (2 EB) Systems Approach on the Shoulders of Giants: The human body is its own ecosystem—much like the ocean—with resilience, hysteresis, synergistic properties, and multi-system dynamics that depend on matrix conditions. Lynchpin: Oligotherapy w/ experimental nano-silver & nano-gold 1st Physical Body (1 PB) GRATITUDE
Together for Lyme SolutionsPart 2: Oligotherapy • Share and encourage dialogue for pragmatic solutions: Problem solving for recovery through a lens of ecology & integrative systems thinking => fresh perspective on Lyme disease
Oligotherapy Using minerals & trace elements as catalysts to maintain physiological functions and restore the body’s natural vitality • Healthy diet is the essential foundation of overall good health • Today’s soil quality & food depleted of essential minerals • Modern pollution & chronic stresses compound problem • Mineral supplementation, in proper form, catalyzes healing
Oligotherapy Minerals and Trace Elements • Human body: 60%-70% solution of minerals & trace elements • Our hydro-mineral composition and relative proportionsare the key • Ocean water a natural source of ALL mineral forms: Ionic, Colloidal, Chelated, Carbon-Organo-Complexed • In 3 billion years Nature found a way to utilize ALL the elements
Oligotherapy & Matrix Matters Broader context from an evolutionary biology, systems perspective 3 Billion Years of Evolution in the Primordial Ocean PRIMORDIAL OCEAN Animal Species Emerges From The Sea Begin Landmass Formation Cellular Life Begins “Water” Covers Earth
RevolutionaryBiologist Oligotherapy & Matrix Matters Broader context from an evolutionary biology, systems perspective “Theonlywaycellularlifecouldleavetheoceanwastotaketheoceanwithit.” • RENÉ QUINTON • “The French Darwin”
All life is cellular All living things are from 50% to over 90% “biological water” The major elements of covalently bonded bio-molecules are C, H, N, O, P, S There is a universal set of small molecules: sugars, amino acids, fatty acids, phospholipids, vitamins and coenzymes Principal macromolecules are proteins, lipids, carbohydrates & nucleic acids There is a universal type of membrane - the lipid bi-layer The flow of energy in living things involves the formation and hydrolysis of phosphate bonds (i.e. ATP) The metabolic reactions of any living species is a subset of a universal network of intermediary metabolism (i.e. glycolysis, Kreb Cycle, electron transport chain) Every replicating cell has genome made of DNA that stores genetic information read out in a sequence of RNA & translated into proteins All living cells have ribosomes, which are the sites of protein synthesis All replicating biological systems give rise to altered phenotype due to mutated genotypes Reactions that proceed at appreciable rates in all living cells are catalyzed by enzymes Oligotherapy & Matrix Matters Seawater: Life’s Architect
The General Case: Original Quinton Plasma Plankton Bloom Harvested – Never Heated Oligotherapy • Seawater – Complex solution of the Periodic Table and “marine factors”. • “Amniotic Fluid” of cellular life • Pischinger: “We now carry the Primordial Sea around within us.” • In Stone: “Terrain is Everything” • Isotonic the medicine – Hypertonic the nutrient • All mineral forms: Ionic, colloidal, chelated, carbon-organo-complexed • Re-establish elements in the milieu interieurto marine “inheritance” Disclosure: I have no financial stake in the Original Quinton company or products but recently began collaborating with their staff for on-going research, including support for my participation in the 2013 Santa Fe Institute Complex Systems program. www.originalquinton.com
Oligotherapy & Matrix Matters Pragmatic solution: Original Quinton • Composition of Quinton marine plasma near identical to human “biological terrain” • Quinton Isotonic • Extra-cellular fluid • Blood plasma “The tides are in our veins” - Robinson Jeffers Disclosure: I have no financial stake in the Original Quinton company or products but recently began collaborating with their staff for on-going research, including support for my participation in the 2013 Santa Fe Institute Complex Systems program. www.originalquinton.com
Oligotherapy & Matrix Matters “The Matrix Matters!” as we say in ecology; in medicine, it has other names: Internal Matrix Liquid Matrix Internal Terrain Biological Terrain Internal Ocean Milieu Interieur Internal Environment … “The internal environment is then the primordial physiological basis of the organism, its‘liquid matrix’.” - Dr. Walter Cannon(Harvard, author of The Wisdom of the Body)
Oligotherapy & Matrix Matters “The Terrain is Everything” - Claude Bernard (1850) Still true today because the Primordial Ocean became our internal terrain 60-70% of us are functional fluids evolved from seawater
Oligotherapy & Matrix Matters To support the Matrix, it’s all about rates of change… Think healing PROCESS! Poor health is like a degraded ocean
Oligotherapy & Matrix Matters To support the Matrix, it’s all about rates of change… Think healing PROCESS! Poor health is analogous to an ocean “Dead Zone” or atrophied estuary with algae overgrowth and depleted oxygen. With an environment this bad, not even the best doctors can save it. So, first, fix the system. Then, the fish/health can return.
Oligotherapy & Matrix Matters To support the Matrix, it’s all about rates of change… Think healing PROCESS! My ocean health analogy = Dr. Cowden’s bathtub
Together for Lyme SolutionsPart 3: Nano-Mineral Tx • Share and encourage dialogue for pragmatic solutions: Problem solving for recovery through a lens of ecology & integrative systems thinking => fresh perspective on Lyme disease
Nano-Mineral Treatments Emerging technologies for new treatment frontiers Nanoparticles: particles <100nm diameter with new or enhanced size-dependent properties, compared with larger particles of the same material. NOT talking man-made chemicals or futuristic bio-nanorobots
Nano-Mineral Treatments Emerging technologies for new treatment frontiers Nanoparticles: particles <100nm diameter with new or enhanced size-dependent properties, compared with larger particles of the same material. New possibilities when metals go nano… Exemplary metals with anti-microbial properties: silver, gold, copper, zinc, platinum, and palladium.
Nano-Mineral Treatments Emerging technologies for new treatment frontiers • Nano-minerals 101: • Nano-structures exist naturally in nature, yet we only recently developed technology to detect • Ionic minerals are naturally nano-minerals • Nanotechnology modifies the surface-area-to-volume ratios of particles • Smaller sizes, greater reactivity • Trade-off between reactivity & instability • Greater reactivity, higher potential energies
Medical History of Silver • Silver used topically & internally for 6,000+ years • Scientifically noted to purify water by 1869 • Colloidal silver used medicinally since 1860s, when coined term to describe silver suspended in a “stable, indeterminate state of matter” Bactericide with risk of argyria (turning blue)
NanoSilver Potential Bactericide without risk of argyria (turning blue) • Nanosilverkills bacteria and lower-level organisms (not mammalian cells) by wreaking havoc in the structure of membrane surfaces. • All nanosilver is colloidal silver. • One nanoparticle binds to multiple Borrelia Burgdorferi (Bb) cells , the spirochetal, Gram negative bacteria causing Lyme disease (Ou et al. 2005). • Colloidal silver acts as a powerful catalyst with ability to attack one-celled organisms (i.e. bacteria, viruses, & fungi) by simultaneous ion and catalectic mechanisms (Ghazvini et al.), blocking respiration and causing the organism to suffocate and die. Qu L. et al., Visulaizingandhesion-induced agglutination of Escherichia coli with mannosyulated nanoparticles, J. NanosciNanotechnol. 2005 Feb; 5(2):319-22. Ghazvini, K., MirzaHesabi, E., Akbarein, M. M., & Crémieux, A. (2008). Antibacterial activity of a malodor neutralizer containing silver nanoparticles. Navid No Journal, 42, 56-60.
NanoSilver Potential (continued) • “Silver kills bacteria by strangling them in a warm and moist environment. Highly bioactive silver ions bind with proteins inside and outside bacterial cell membranes, thus inhibiting respiration and reproduction” (Wasif and Laga 2009). • Nanosilverparticles attack particular microbes, using species-specific mechanisms (Song et al 2006, Ruparelia 2008). • Nanosilverprevents biofilm formation (Gibbins and Warner 2005). Wasif, A. I., & Laga, S. K. (2009). Use of nano silver as an antimicrobial agent for cotton. AUTEX Res. J, 9(5), 13. Song, H. Y., Ko, K. K., Oh, I. H., & Lee, B. T. (2006). Fabrication of silver nanoparticles and their antimicrobial mechanisms. Eur Cells Mater, 11(Suppl 1), 58. Ruparelia, J. P., Chatterjee, A. K., Duttagupta, S. P., & Mukherji, S. (2008). Strain specificity in antimicrobial activity of silver and copper nanoparticles. ActaBiomaterialia, 4(3), 707-716. Gibbins, B., & Warner, L. (2005). The role of antimicrobial silver nanotechnology. Medical Device & Diagnostic Industry Magazine, 1, 1-2.
NanoSilver Potential (continued) • Antimicrobial mechanisms of nanosilver include: • Inhibition of cell wall synthesis, protein synthesis, & nucleic acid synthesis (Lara et al., 2010). • Cell-wall “pitting” (Choi et al., 2008). • Accumulation of silver nanoparticles in bacterial membrane (Elechiguerra et al. 2005). • On-going investigation required to fully understand mechanisms (Marambio-Jones & Hoek 2010). Lara, H. H., Ayala-Núnez, N. V., Turrent, L. D. C. I., & Padilla, C. R. (2010). Bactericidal effect of silver nanoparticles against multidrug-resistant bacteria. World Journal of Microbiology and Biotechnology, 26(4), 615-621. Choi, O et al. (2008). The inhibitory effect of silver nanoparticles, silver ions and silver chloride colloids on microbial growth, in Water Red, 42(12): 3066-74. Elechiguerra, J. L., Burt, J. L., Morones, J. R., Camacho-Bragado, A., Gao, X., Lara, H. H., & Yacaman, M. J. (2005). Interaction of silver nanoparticles with HIV-1. J nanobiotechnol, 3(6), 1-10. Marambio-Jones, C., & Hoek, E. M. (2010). A review of the antibacterial effects of silver nanomaterials and potential implications for human health and the environment. Journal of Nanoparticle Research, 12(5), 1531-1551.
NanoSilver Potential (continued) • Antimicrobial properties of nanosilver in a variety of medical applications including: • Topical silver widely used in wound & burn treatment to prevent scarring & enhance healing. (Gibbins& Warner 2005). • Silver-containing dressings to combat MRSA (Thomas 2004). • Widely used in silver-based dressings & silver coated medicinal devices (e.g., nanogels, nanolotions, & catheters) (Rai 2009, Baratchi et al. 2009, Estevez & Erlichman 2011). Gibbins, B., & Warner, L. (2005). The role of antimicrobial silver nanotechnology. Medical Device & Diagnostic Industry Magazine, 1, 1-2. Thomas, S. (2004). MRSA and the use of silver dressings: overcoming bacterial resistance. World Wide Wounds. Rai, M., Yadav, A., & Gade, A. (2009). Silver nanoparticles as a new generation of antimicrobials. Biotechnology advances, 27(1), 76-83. Baratchi, S., Kanwar, R. K., Khoshmanesh, K., Vasu, P., Ashok, C., Hittu, M., ... & Kanwar, J. R. (2009). Promises of nanotechnology for drug delivery to brain in neurodegenerative diseases. Current Nanoscience, 5(1), 15-25. Estevez, A. Y., & Erlichman, J. S. (2011). Cerium Oxide Nanoparticles for the Treatment of Neurological Oxidative Stress Diseases. brain, 28, 30.
NanoSilver Potential Application for Lyme & Tick-Borne Coinfections • Few studies, if any, with patients evaluate the efficacy of nanosilver to treat Lyme, specifically, and tick borne diseases, generally. • Nonetheless, anecdotal case studies (like me) & peer-reviewed studies on general antimicrobial efficacy suggest that nanosilvercan successfully treat Lyme infections—both alone and in combination with antibiotics—because of: • low risk • high effectiveness • microbes’ inability to evolve a silver-resistant form
NanoSilver Potential Improved Antibiotic Efficacy • Laboratory studies demonstrate a synergistic antibacterial effects between nanosilver& antibiotics (Shahverdi 2007): • penicillin G • amoxicillin • erythromycin • clindamycin • vancomycin Shahverdi, A. R., Fakhimi, A., Shahverdi, H. R., & Minaian, S. (2007). Synthesis and effect of silver nanoparticles on the antibacterial activity of different antibiotics against Staphylococcus aureusand Escherichia coli. Nanomedicine: Nanotechnology, Biology and Medicine, 3(2), 168-171. May aid transport across blood-brain barrier and/or penetrate biofilms for increased antibiotic efficacy
Medical History of Gold • Gold used topically & internally for 5,000+ years • Gold in dentistry ~4,500 years ago • Anti-inflammatory, used to treat sore joints in 1900s, as well as arthritis in 20th Century Side effects: Skin rash/sores, metallic taste, thinning hair
NanoGold Potential Extremely good catalyst, acts as a semiconductor • Potential applications: • Rapid diagnosis technologies, including diagnosis of Lyme disease, rickettsioses, ehrlichioses, and anaplasmosis. • Cancer treatments without surgery, “nanobullets” that travel inside cancer cells and bind to internal structures to prevent cell division. • Telomeres extension for increased longevity & anti-aging • Synergisms with nanosilverfor increased antimicrobial properties • Synergisms with nanosilver to mitigate Lyme symptoms & inflammation responses, possibly prevent Herxheimer reactions New possibilities when metals go nano…
Together for Lyme SolutionsPart 4: The Lyme Cure • Share and encourage dialogue for pragmatic solutions: Problem solving for recovery through a lens of ecology & integrative systems thinking => fresh perspective on Lyme disease
YES we can! The Lyme Cure No silver bullet, yet people CAN heal if they believe recovery possible 5th Spirit (5 SB) 4th Intuitive (4 IB) 3rd Mental (3 MB) 2nd Energy Body (2 EB) 1st Physical Body (1 PB) • 100% recovery is an ACTIVE PROCESS with commitment on ALL levels
YES we can! The Lyme Cure Patients & the medical community must overcome “4 min mile” barrier to full Lyme recovery 5th Spirit (5 SB) 4th Intuitive (4 IB) 3rd Mental (3 MB) 2nd Energy Body (2 EB) 1st Physical Body (1 PB) • HoneyHoneyHealing.org
YES we can! The Lyme Cure “We can’t solve problems by using the same kind of thinking we used when we created them” - Albert Einstein 5th Spirit (5 SB) 4th Intuitive (4 IB) 3rd Mental (3 MB) Infinite possibilities through innovation… 2nd Energy Body (2 EB) 1st Physical Body (1 PB) • HoneyHoneyHealing.org
Problem solving is a team effort & I’ve had a great team. Thank you! for support from Gratitude! Questions Welcome! Stanford University (Stanford Medical School still needs Lyme education) • E-IPER Department • Woods Institute for the Environment • Hopkins Marine Station, Biology Department • Terry Root & Steve Schneider, “The Patient from Hell” • Don Kennedy • Alfred Spormann • Cheryl Koopman Medical Support • Columbia University Lyme & Tick-Borne Diseases, NY • Dr. Klinghardt & Klinghardt Academy • Foothill Chiropractic & Wellness, Los Altos, CA • Pacific Frontier Medical, Redwood City, CA • Theocentric Holistic Healing & Counseling, WPB, FL • True North, Falmouth, ME Visionary Friends • Lee Cowden, Bill Gonseaux, & Lisa Wade, ACIM • Rob Slovak, Original Quinton • Wayne Harris, Advanced BioNutritional Research HoneyHoneyHealing.org Hook, Line and Thinker by Ray Troll