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Paul D.R.. Spragggs etal. The Journal of Laryngology and Otology July 1995, Vol. 109, pp. 618-621.

A PROSPECTIVE RANDOMIZED STUDY TO ASSESS THE EFFICACY OF POST-OPERATIVE NASAL MEDICATION AFTER ENDONASAL SURGERY. Paul D.R.. Spragggs etal. The Journal of Laryngology and Otology July 1995, Vol. 109, pp. 618-621. Treatment Groups .Alkaline nasal douche (n = 19) .Betnosol drops (n = 17)

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Paul D.R.. Spragggs etal. The Journal of Laryngology and Otology July 1995, Vol. 109, pp. 618-621.

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  1. A PROSPECTIVE RANDOMIZED STUDY TO ASSESS THE EFFICACY OF POST-OPERATIVE NASAL MEDICATION AFTER ENDONASAL SURGERY • Paul D.R.. Spragggs etal. • The Journal of Laryngology and Otology July 1995, Vol. 109, pp. 618-621. • Treatment Groups • .Alkaline nasal douche (n = 19) • .Betnosol drops (n = 17) • .0.5% Eplidrine drops (n = 20) • .Control (n= 19)

  2. Outcome • Nasal stuffiness as measured on a visual analogue scale

  3. Analysis • Mann whitney U. Test • Glass rank biserial correlation • Significant ( P<0.05) differences were found at all time intervals

  4. Conclusion • The use of these treatments should be encouraged to both improve the sensation of nasal patency and also aid clearance of debris from the nasal fossae.

  5. Mean Visual Analogue Scores (VAS) and Standard Deviations (SD) for each group.

  6. EFFICIENCY OF VIT. A. IN REDUCING PRE-SCHOOL CHILD MORTALITY 6 – 11 MONTHS Vit. A Control RR Malnourished 4.6% 6.6% 1.4 Well nourished 1.3% 1.8% 1.4 (3.5) (3.7) 12 – 72 MONTHS Malnourished 6% 8% 1.3 Well nourished 0.4% 0.7% 1.75 (15) (11.4)

  7. Effect of passive smoking on Ischaemic heart disease mortality of non smokers. A prospective study Garland et. al American Journal of Epidemiology Vol. 121. No. 5, 1985.

  8. Subjects: Married women who never smoked aged 50 – 79. Exposure variable: Husbands’ smoking habit a)Never - 203 b)Former - 395 c)Current - 97 Follow up: 10 years Analysis: Adjustments done using Cox’s proportional Hazards model. Finding: Wives of current / past smoker had 14.9 time greater risk of CHD deaths Recommendation: Ban smoking in closed places.

  9. Age adjusted 10 year mortality rateaccording to husband’s smoking status Never Former Current (n = 203) ( n = 395) (n = 97) CHD Death rates 1.2% 3.6% 2.7% All causes 11% 11% 13.3%

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