1 / 1

IgG-IgG

IgG-IgG is a type of bispecific antibody conjugates, antibody-antibody conjugates.

bellasmith12
Download Presentation

IgG-IgG

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. IgG-IgG IgG-IgG is a type of bispecific antibody conjugates, antibody-antibody conjugates. Crosslinking of IgGs is a direct approach to generate BsAbs. It is generated by conjugating two full length antibodies. IgG- IgG conjugate has a MW of ~300 kDa and is bivalent for each antigen. Usually, the generation of IgG-IgG conjugate relies on the amino- reactive reagents. And the widely used crosslinkers include SPDP, Traut’s reaget/SMCC, etc. In some conditions, IgG-IgG conjugates generated are high heterogeneity, which may be a backbone to get high-purity homogeneous antibody.

More Related