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Cholingeric Agonist Practice Questions. Pretest question. The enzyme that is inhibited by echothiophate iodide is a. Tyrosine hydroxylase b. Acetylcholinesterase (AChE) c. Catechol -O-methyltransferase (COMT) d. Monoamine oxidase (MAO) e. Carbonic anhydrase. Pretest question.
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Pretest question • The enzyme that is inhibited by echothiophate iodide is • a. Tyrosine hydroxylase • b. Acetylcholinesterase (AChE) • c. Catechol-O-methyltransferase (COMT) • d. Monoamine oxidase (MAO) • e. Carbonic anhydrase
Pretest question • The reversible cholinesterase inhibitor indicated in the treatment of Alzheimer’s disease is • a. Tacrine • b. Edrophonium • c. Neostigmine • d. Pyridostigmine • e. Ambenonium
Pretest question • All of the following drugs are used topically in the treatment of chronic wide-angle glaucoma. Which of these agents reduces intraocular pressure by decreasing the formation of the aqueous humor? • a. Timolol • b. Echothiophate • c. Pilocarpine • d. Isofluorphate • e. Physostigmine
Pretest Question • The cholinomimetic drug that is useful for treating postoperative abdominal distention and gastric atony is • a. Acetylcholine (ACh) • b. Methacholine • c. Carbachol • d. Bethanechol • e. Pilocarpine
Pretest question Pralidoxime chloride is a drug that • a. Reduces the vesicular stores of catecholamines in adrenergic and dopaminergic neurons • b. Blocks the active transport of choline into cholinergic neurons • c. Reactivates cholinesterases that have been inhibited by organophosphate cholinesterase inhibitors • d. Stimulates the activity of phospholipase C with increased formation of inositol • triphosphate • e. Inhibits the reuptake of biogenic amines into nerve terminals
Pretest Question • The cholinesterase inhibitor that is used in the diagnosis of myasthenia gravis is • a. Edrophonium chloride • b. Ambenonium chloride • c. Malathion • d. Physostigmine salicylate • e. Pyridostigmine bromide
Pretest Question • Of the following effects, which is not elicited by activation of the parasympathetic nervous system? • a. Decreased heart rate • b. Increased tone of longitudinal smooth muscles of the intestine • c. Contraction of skeletal muscles • d. Contraction of the detrusor of the urinary bladder • e. Secretion of fluid from the lacrimal glands
Pretest Question • Which one of these drugs are used in Glaucoma? • a. Pilocarpine • b. Methylphenidate • c. Propranolol • d. Ritodrine • e. Phenoxybenzamine
Practice Question Which of the following would not be expected as a sign of cholinesterase inhibitor-insecticide poisoning. • Mydriasis • Increased Salivation • Increased bowel sounds • Urinary urgency • Skeletal muscle spasms Paralysis
Practice Question In the previous question, what would be the treatment for this patient? • Atropine and epinephrine • Epinephrine and Isoproterenol • Norepinephrine and Propranolol • Atropine and Praxilodime • Prolidoxine and Propanolol
Practice Question Which of the following drugs can be used to reduce IOP in treatment of Glaucoma? • Pilocarpine • Azetozelomide • Neostigmine • Timolol • All of the above
Practice Question • Which of the following cholinesterase inhibitors has the shortest duration of action? • Neostigmine • Phyostigmine • Edrophonium • Echothiophate • Trimethaphan