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1. Hormones & Sexual Behavior Lecture 24
3. Female behavior: rats Receptive - lordosis
head down
haunches up
Proceptive
ear wiggling
darting
Hopping ~
4. Male behavior: rats Mounts
no testosterone ? no mounting
Intromits several times
Ejaculates
4-5 times
5 min refractory period ~
5. Organizational Effects of Hormones SDN & SNB
Critical periods
Humans - prenatal
Rats - perinatal
easily manipulated ~
6. Hormones: Sexual Behavior Castrate XY males at birth
Later...
testosterone ? no male behavior
estrogen?
lordosis
Brain not masculinized ~
7. Hormones: Sexual Behavior Ovariectomize female at birth
give testosterone
Later...
estrogens ? no female behavior
testosterone ? male behavior
Brain masculinized ~
8. Human Sexual Behavior No stereotypical M & F behaviors
Men are like rats
T plays a activational role
Castration
decline in sexual behaviors
variable rate
Role of oxytocin?
probably not
knockout mice ~
9. Hormones - Women Estrogen & Progesterone
no activational effects
Ovariectomy has no effect
Some fx on willingness to copulate
increased during ovulation
E & P are high ~
10. Hormones - Women Testosterone levels
correlated with frequency of intercourse
Oxytocin
uterine and vaginal contractions
sensations associated with orgasm ~
11. Brain Mechanisms: Rats Medial preoptic area
lesion SDN ? no M sexual behavior
NOT sexual motivation
Bar press for female ~
12. Brain Mechanisms: Rats Ventromedial nucleus
lesion- no female sexual behavior
Masculinizes by preventing cell death
Amygdala
lesion ? increased sexual behavior
Indiscriminate ~
13. Homosexuality Sex hormones role?
rats - yes
Humans?
NOT SURE
Learning experiences?
or biologically determined? ~
14. Biological Factors Levels of circulating sex hormones?
No
Differences in brain structure?
Perhaps - Where? ~
15. Homosexuality Simon LeVay
Brains of male AIDS victims
Anterior Hypothalamus
Anterior commissure
SDN (rats)
Humans: 3rd interstitial nucleus ~
16. Anterior commissure larger in females
Similar relationship ~
17. Homosexuality 2 Hypotheses 1. Androgen levels
low in XY fetuses that ? gay
high in XX fetuses ? lesbian
2. Genetic differences in fetal brains response to androgens
Xq28 - tip of the X chromosome
shared by large % of gay brothers ~