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1. Beth Rutkowski, M.P.H.
finnerty@ucla.edu
Pacific Southwest Addiction Technology Transfer Center UCLA Integrated Substance Abuse Programs
2. Consequences to the Brain
6. PET Scan of Long-Term Impact of Methamphetamine on the Brain
7. Decreased dopamine transporter binding in METH users resembles that in Parkinson’s Disease If DAT is decreased in young METH users (almost to that observed in Parkinson’s Disease), and DAT decreases with age, may we see an increase in the number of Parkinsonian patients over time?
If DAT is decreased in young METH users (almost to that observed in Parkinson’s Disease), and DAT decreases with age, may we see an increase in the number of Parkinsonian patients over time?
9.
Cognitive and
Memory Effects
10. Differences between Stimulant and Comparison Groups on tests requiring perceptual speed
11. Memory Difference between Stimulant and Comparison Groups
12. Longitudinal Memory Performance
16. How much does the brain heal?
17. PET Scan of Long-Term Meth Brain Damage
19. Partial Recovery of Brain Metabolism in Methamphetamine (METH) Abuserafter Protracted Abstinence
20. Acute and Long-Term Effects of the Methamphetamine Abuse A Quick Review:
21. MethamphetamineAcute Physical Effects Increases
Heart rate
Blood pressure
Pupil size
Respiration
Sensory acuity
Energy
22. MethamphetamineAcute Psychological Effects Increases
Confidence
Alertness
Mood
Sex drive
Energy
Talkativeness Decreases
Boredom
Loneliness
Timidity
23. Long-Term Effects of Methamphetamine
24. MethamphetamineChronic Physical Effects Tremor
Weakness
Dry mouth
Weight loss
Cough
Sinus infection
25. MethamphetamineChronic Psychological Effects Confusion
Concentration
Hallucinations
Fatigue
Memory loss
Insomnia
26. Local Infections
28. Faces of Methamphetamine Images courtesy Multnomah County Sheriff’s Office
29. Meth Mouth Rotting of teeth around the gums
Process may involve lack of saliva production or qualities of methamphetamine or its constituents
Smoking/snorting problems
Bruxism; Rampant caries
30. Infective Endocarditis (i.e., staphylococcus aurcus)
Frequent among IDUs
8-16% of hospital admissions for IDUs
Organism colonizes skin, also includes drug, adulterants, packaging, fluids
Occurs mostly to right side of heart
Most common symptom is chest pain, cough, fever, chills, arthralgia
Antibiotic treatment or surgery
Infective Endocarditis (i.e., staphylococcus aurcus)
Frequent among IDUs
8-16% of hospital admissions for IDUs
Organism colonizes skin, also includes drug, adulterants, packaging, fluids
Occurs mostly to right side of heart
Most common symptom is chest pain, cough, fever, chills, arthralgia
Antibiotic treatment or surgery
31. MATRIX MODEL TREATMENT
32. STAGES OF RECOVERY - STIMULANTS
37. Successful Outpatient Treatment Predictors Durations over 90 days (with continuing care for another 9 months).
Techniques and clinic practices that improve treatment retention are critical.
Treatment should include 3-5 clinic visits per week for at least 90 days.
38. Successful Outpatient Treatment Predictors Employ evidence-based practices [i.e., CBT, CM, Community Reinforcement Approach, Motivational Interviewing, Matrix Model].
Family involvement and 12-step programs appear to improve outcome.
Urine testing (at least weekly is recommended)
39. Special treatment consideration should be made for the following groups of individuals: Female MA users (higher rates of depression; very high rates of previous and present sexual and physical abuse; responsibilities for children).
Injection MA users (very high rates of psychiatric symptoms; severe withdrawal syndromes; high rates of hepatitis).
MA users who take MA daily or in very high doses.
40. Special treatment consideration should be made for the following groups of individuals: Homeless, chronically mentally ill and/or individuals with high levels of psychiatric symptoms at admission.
Individuals under the age of 21.
Gay men (at very high risk for HIV and hepatitis).